Ankylosing Spondylitis

HLA-B27 alters BMP/TGFβ signalling in Drosophila, revealing putative pathogenic mechanism for spondyloarthritis
Benjamin Grandon, Aurore Rincheval-Arnold, Nadège Jah, Jean-Marc Corsi, Luiza M Araujo, Simon Glatigny, Erwann Prevost, Delphine Roche, Gilles Chiocchia, Isabelle Guénal, Sébastien Gaumer, Maxime Breban

Annals of the Rheumatic Diseases Dec 2019, 78 (12) 1653-1662; DOI: 10.1136/annrheumdis-2019-215832
Shotgun metagenomics reveals an enrichment of potentially cross-reactive bacterial epitopes in ankylosing spondylitis patients, as well as the effects of TNFi therapy upon microbiome composition
Jian Yin, Peter Richard Sternes, Mingbang Wang, Jing Song, Mark Morrison, Ting Li, Ling Zhou, Xin Wu, Fusheng He, Jian Zhu, Matthew A Brown, Huji Xu

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-215763; DOI: 10.1136/annrheumdis-2019-215763
Efficacy and safety of ixekizumab through 52 weeks in two phase 3, randomised, controlled clinical trials in patients with active radiographic axial spondyloarthritis (COAST-V and COAST-W)
Maxime Dougados, James Cheng-Chung Wei, Robert Landewé, Joachim Sieper, Xenofon Baraliakos, Filip Van den Bosch, Walter P Maksymowych, Joerg Ermann, Jessica A Walsh, Tetsuya Tomita, Atul Deodhar, Désirée van der Heijde, Xiaoqi Li, Fangyi Zhao, Clinton C Bertram, Gaia Gallo, Hilde Carlier, Lianne S Gensler

Annals of the Rheumatic Diseases Nov 2019, annrheumdis-2019-216118; DOI: 10.1136/annrheumdis-2019-216118
Development of ASAS quality standards to improve the quality of health and care services for patients with axial spondyloarthritis
Uta Kiltz, Robert B M Landewé, Désirée van der Heijde, Martin Rudwaleit, Michael H Weisman, Nurullah Akkoc, Annelies Boonen, Jan Brandt, Philippe Carron, Maxime Dougados, Laure Gossec, Merryn Jongkees, Pedro M Machado, Helena Marzo-Ortega, Anna Molto, Victoria Navarro-Compán, Karin Niederman, Percival Degrava Sampaio-Barros, Gleb Slobodin, Filip E Van den Bosch, Astrid van Tubergen, Salima van Weely, Dieter Wiek, Juergen Braun

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-216034; DOI: 10.1136/annrheumdis-2019-216034
Unmet need in rheumatology: reports from the Targeted Therapies meeting 2019
Kevin L Winthrop, Michael E Weinblatt, Joan Bathon, Gerd R Burmester, Philip J Mease, Leslie Crofford, Vivian Bykerk, Maxime Dougados, James Todd Rosenbaum, Xavier Mariette, Joachim Sieper, Fritz Melchers, Bruce N Cronstein, Ferry C Breedveld, Joachim Kalden, Josef S Smolen, Daniel Furst

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-216151; DOI: 10.1136/annrheumdis-2019-216151
Gut-derived CD8⁺ tissue-resident memory T cells are expanded in the peripheral blood and synovia of SpA patients
Giuliana Guggino, Aroldo Rizzo, Daniele Mauro, Federica Macaluso, Francesco Ciccia

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-216456; DOI: 10.1136/annrheumdis-2019-216456
Response to: ‘Diabetes mellitus in ankylosing spondylitis’ by Lee and Song
Shih-Wei Lai, Yu-Hung Kuo, Kuan-Fu Liao

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-216429; DOI: 10.1136/annrheumdis-2019-216429
Diabetes mellitus in ankylosing spondylitis
Young Ho Lee, Gwan Gyu Song

Annals of the Rheumatic Diseases Oct 2019, annrheumdis-2019-216335; DOI: 10.1136/annrheumdis-2019-216335
Evidence that tissue resident human enthesis γδT-cells can produce IL-17A independently of IL-23R transcript expression
Richard James Cuthbert, Abdulla Watad, Evangelos M Fragkakis, Robert Dunsmuir, Peter Loughenbury, Almas Khan, Peter A Millner, Adam Davison, Helena Marzo-Ortega, Darren Newton, Charlie Bridgewood, Dennis G McGonagle

Annals of the Rheumatic Diseases Nov 2019, 78 (11) 1559-1565; DOI: 10.1136/annrheumdis-2019-215210
Integrin and transcriptomic profiles identify a distinctive synovial CD8+ T cell subpopulation in spondyloarthritis
Zoya Qaiyum, Eric Gracey, YuChen Yao, Robert D Inman

Annals of the Rheumatic Diseases Nov 2019, 78 (11) 1566-1575; DOI: 10.1136/annrheumdis-2019-215349

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