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BMJ Journals

Online First

October 18, 2021

Autoimmunity
Rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome shared megakaryocyte expansion in peripheral blood

Yukai Wang, Xuezhen Xie, Chengpeng Zhang, Miaotong Su, Sini Gao, Jing Wang, Changhao Lu, Qisheng Lin, Jianqun Lin, Marco Matucci-Cerinic, Daniel E Furst, Guohong Zhang

doi: 10.1136/annrheumdis-2021-220066
Criteria
Mechanosensitive TRPV4 is required for crystal-induced inflammation

Zhou Lan, Lvyi Chen, Jing Feng, Zili Xie, Zhiyong Liu, Fang Wang, Peng Liu, Xueping Yue, Lixia Du, Yonghui Zhao, Pu Yang, Jialie Luo, Zhe Zhu, Xueming Hu, Liang Cao, Ping Lu, Rajan Sah, Kory Lavine, Brian Kim, Hongzhen Hu

doi: 10.1136/annrheumdis-2021-220295

October 16, 2021

Viewpoint
No efficacy of anti-IL-23 therapy for axial spondyloarthritis in randomised controlled trials but in post-hoc analyses of psoriatic arthritis-related ‘physician-reported spondylitis’?

Juergen Braun, Robert BM Landewé

doi: 10.1136/annrheumdis-2021-221422

October 11, 2021

Letter
Inactivated vaccines may not provide adequate protection in immunosuppressed patients with rheumatic diseases
Free

Padmanabha Shenoy, Sakir Ahmed, Aby Paul, Somy Cherian, Anuroopa Vijayan, Sageer AS Babu, Aswathy Sukumaran

doi: 10.1136/annrheumdis-2021-221496

October 08, 2021

Epidemiology
Serious infections in patients with rheumatoid arthritis and psoriatic arthritis treated with tumour necrosis factor inhibitors: data from register linkage of the NOR-DMARD study

Ingrid Egeland Christensen, Siri Lillegraven, Pawel Mielnik, Gunnstein Bakland, Liz Loli, Joe Sexton, Till Uhlig, Tore K Kvien, Sella A Provan

doi: 10.1136/annrheumdis-2021-221007
Letter
Fat mass and response to TNFα blockers in early axial spondyloarthritis: an analysis of the DESIR cohort

Anna Molto, Solange Tang, Bernard Combe, Maxime Dougados, Pascal Richette

doi: 10.1136/annrheumdis-2021-221001
Rheumatoid arthritis
Splicing machinery is impaired in rheumatoid arthritis, associated with disease activity and modulated by anti-TNF therapy

Alejandro Ibáñez-Costa, Carlos Perez-Sanchez, Alejandra María Patiño-Trives, Maria Luque-Tevar, Pilar Font, Ivan Arias de la Rosa, Cristobal Roman-Rodriguez, Mª Carmen Abalos-Aguilera, Carmen Conde, Antonio Gonzalez, Sergio Pedraza-Arevalo, Mercedes del Rio-Moreno, Ricardo Blazquez-Encinas, Pedro Segui, Jerusalem Calvo, Rafaela Ortega Castro, Alejandro Escudero-Contreras, Nuria Barbarroja, Mª Angeles Aguirre, Justo P Castaño-Fuentes, Raul M Luque, Eduardo Collantes-Estevez, Chary Lopez-Pedrera

doi: 10.1136/annrheumdis-2021-220308

October 07, 2021

Correspondence response
Response to: ‘Correspondence on ‘What comes after the lockdown? Clustering of ANCA-associated vasculitis: single-centre observation of a spatiotemporal pattern’’ by Hakroush and Tampe
Free

Philipp Gauckler, Andreas Kronbichler

doi: 10.1136/annrheumdis-2020-219696
Correspondence
Correspondence on ‘Glucosamine and O-GlcNAcylation: a novel immunometabolic therapeutic target for OA and chronic, low-grade systemic inflammation?’
Free

Socrates Angelides, Nicholas Manolios

doi: 10.1136/annrheumdis-2020-219694
Correspondence
Correspondence on ‘Non-surgical and surgical treatments for rotator cuff disease: a pragmatic randomised clinical trial with 2-year follow-up after initial rehabilitation’
Free

Pietro Randelli, Lavinia Agra Coletto, Alessandra Menon, Roberto Caporali

doi: 10.1136/annrheumdis-2020-219751
Correspondence response
Response to: ‘Correspondence on ‘Risk factors for hospital admissions related to COVID-19 in patients with autoimmune inflammatory rheumatic diseases’’ by Aydin et al
Free

Dalifer Dayanira Freites Nuñez, Leticia Leon, Arkaitz Mucientes, Luis Rodriguez-Rodriguez, Judit Font Urgelles, Alfredo Madrid García, Jose Ignacio Colomer, Juan A Jover, Benjamín Fernandez-Gutierrez, Lydia Abasolo

doi: 10.1136/annrheumdis-2020-219580
Correspondence
Correspondence on ‘Clinical course of coronavirus disease 2019 (COVID-19) in a series of 17 patients with systemic lupus erythematosus under long-term treatment with hydroxychloroquine’
Free

Sarthak Gupta, Shuichiro Nakabo, Jun Chu, Sarfaraz Hasni, Mariana J Kaplan

doi: 10.1136/annrheumdis-2020-219648
Correspondence response
Response to: ‘Correspondence on ‘Critical role of neutrophil extracellular traps (NETs) in patients with Behcet’s disease’’ by Chen et al
Free

Alexandre Le Joncour, David Saadoun, Yacine Boulaftali

doi: 10.1136/annrheumdis-2020-219484
Correspondence
Correspondence on ‘Interleukin 6 receptor inhibition in primary Sjögren syndrome: a multicentre double-blind randomised placebo-controlled trial’
Free

Bin Wang, Shiju Chen, Jingxiu Xuan, Yan Li, Qing Zheng, Xinwei Zhang, Yuan Liu, Guixiu Shi

doi: 10.1136/annrheumdis-2020-219666
Correspondence
Correspondence on ‘Risk of venous thromboembolism in knee, hip and hand osteoarthritis: a general population-based cohort study’
Free

Tsung-Kun Lin, Lung-Fa Pan, Gwo-Ping Jong

doi: 10.1136/annrheumdis-2020-219733
Correspondence response
Response to: ‘Correspondence on “Glucosamine and O-GlcNAcylation: a novel immunometabolic therapeutic target for OA and chronic, low-grade systemic inflammation?’ by Angelides and Manolios
Free

Gabriel Herrero-Beaumont, Raquel Largo

doi: 10.1136/annrheumdis-2020-219721
Correspondence response
Response to: ‘Correspondence on ‘Rituximab as therapy to induce remission after relapse in ANCA-associated vasculitis’’ by Parikh et al
Free

Rona M Smith, Peter A Merkel, David Jayne

doi: 10.1136/annrheumdis-2020-219329
Miscellaneous
2021 update of the EULAR points to consider on the use of immunomodulatory therapies in COVID-19
Free

Alessia Alunno, Aurélie Najm, Pedro M Machado, Heidi Bertheussen, Gerd-Rüdiger R Burmester, Francesco Carubbi, Gabriele De Marco, Roberto Giacomelli, Olivier Hermine, John D Isaacs, Isabelle Koné-Paut, César Magro-Checa, Iain B McInnes, Pier Luigi Meroni, Luca Quartuccio, A V Ramanan, Manuel Ramos-Casals, Javier Rodríguez Carrio, Hendrik Schulze-Koops, Tanja A Stamm, Sander W Tas, Benjamin Terrier, Dennis G McGonagle, Xavier Mariette

doi: 10.1136/annrheumdis-2021-221366
Correspondence response
Response to: ‘Correspondence on ‘Prevalence and clinical outcomes of COVID-19 in patients with autoimmune diseases: a systematic review and meta-analysis’’ by Yang et al
Free

Shintaro Akiyama, Shadi Hamdeh, Dejan Micic, Atsushi Sakuraba

doi: 10.1136/annrheumdis-2021-219855
Correspondence response
Response to: ‘Correspondence on ‘Risk of venous thromboembolism in knee, hip and hand osteoarthritis: a general population-based cohort study’’ by Lin et al
Free

Chao Zeng, Zidan Yang, Guanghua Lei, Yuqing Zhang

doi: 10.1136/annrheumdis-2020-219747
Correspondence
Correspondence on ‘Machine learning algorithms reveal unique gene expression profiles in muscle biopsies from patients with different types of myositis’
Free

Satoshi Takanashi

doi: 10.1136/annrheumdis-2020-219677
Correspondence response
Response to: ‘Correspondence on ‘Preliminary predictive criteria for COVID-19 cytokine storm’’ by Tampe et al
Free

Roberto Caricchio, Marcello Gallucci, Chandra Dass, Xinyan Zhang, Stefania Gallucci, David Fleece, Michael Bromberg, Gerard J Criner

doi: 10.1136/annrheumdis-2020-219720
Correspondence response
Response to: ‘Correspondence on ‘Systemic sclerosis and the COVID-19 pandemic: World Scleroderma Foundation preliminary advice for patient management’’ by Snarskaya and Vasileva
Free

Cosimo Bruni, Marco Matucci-Cerinic

doi: 10.1136/annrheumdis-2020-219533
Correspondence response
Response to: ‘Correspondence on ‘Historically controlled comparison of glucocorticoids with or without tocilizumab versus supportive care only in patients with COVID-19- associated cytokine storm syndrome: results of the CHIC study’’ by Calvo-Aranda et al
Free

Sofia Ramiro, Rémy Mostard, Robert BM Landewé

doi: 10.1136/annrheumdis-2020-219534

October 06, 2021

Review
Axial spondyloarthritis

Victoria Navarro-Compán, Alexandre Sepriano, Bassel El-Zorkany, Désirée van der Heijde

doi: 10.1136/annrheumdis-2021-221035
Spondyloarthritis
Does biologic therapy impact the development of PsA among patients with psoriasis?

Elana Meer, Joseph F Merola, Robert Fitzsimmons, Thorvardur Jon Love, Shiyu Wang, Daniel Shin, Yong Chen, Sharon Xie, Hyon Choi, Yuqing Zhang, Jose U Scher, C T Ritchlin, Joel M Gelfand, Alexis Ogdie

doi: 10.1136/annrheumdis-2021-220761
Systemic lupus erythematosus
B-cell depletion with obinutuzumab for the treatment of proliferative lupus nephritis: a randomised, double-blind, placebo-controlled trial

Richard A Furie, Gustavo Aroca, Matthew D Cascino, Jay P Garg, Brad H Rovin, Analia Alvarez, Hilda Fragoso-Loyo, Elizabeth Zuta-Santillan, Thomas Schindler, Paul Brunetta, Cary M Looney, Imran Hassan, Ana Malvar

doi: 10.1136/annrheumdis-2021-220920
Rheumatoid arthritis
Incidence and risk factors for herpes zoster in patients with rheumatoid arthritis receiving upadacitinib: a pooled analysis of six phase III clinical trials

Kevin L Winthrop, Peter Nash, Kunihiro Yamaoka, Eduardo Mysler, Nasser Khan, Heidi S Camp, Yanna Song, Jessica L Suboticki, Jeffrey R Curtis

doi: 10.1136/annrheumdis-2021-220822

October 05, 2021

Systemic lupus erythematosus
Genomic sequencing and functional analyses identify MAP4K3/GLK germline and somatic variants associated with systemic lupus erythematosus

Huai-Chia Chuang, Wei-Ting Hung, Yi-Ming Chen, Pu-Ming Hsu, Jeng-Hsien Yen, Joung-Liang Lan, Tse-Hua Tan

doi: 10.1136/annrheumdis-2021-221010

October 04, 2021

Rheumatoid arthritis
Baseline predictors of different types of treatment success in rheumatoid arthritis

Dafne Capelusnik, Daniel Aletaha

doi: 10.1136/annrheumdis-2021-220853
Systemic lupus erythematosus
BNT162b2 vaccine-induced humoral and cellular responses against SARS-CoV-2 variants in systemic lupus erythematosus

Quentin Moyon, Delphine Sterlin, Makoto Miyara, François Anna, Alexis Mathian, Raphael Lhote, Pascale Ghillani-Dalbin, Paul Breillat, Sasi Mudumba, Sophia de Alba, Fleur Cohen-aubart, Julien Haroche, Micheline Pha, Thi Huong Du Boutin, Hedi Chaieb, Pedro Macedo Flores, Pierre Charneau, Guy Gorochov, Zahir Amoura

doi: 10.1136/annrheumdis-2021-221097

October 01, 2021

Rheumatoid arthritis
Loss of balance between protective and pro-inflammatory synovial tissue T-cell polyfunctionality predates clinical onset of rheumatoid arthritis

Achilleas Floudas, Nuno Neto, Carl Orr, Mary Canavan, Phil Gallagher, Conor Hurson, Michael G Monaghan, Sunil Nagpar, Ronan H Mullan, Douglas J Veale, Ursula Fearon

doi: 10.1136/annrheumdis-2021-220458

September 28, 2021

Viewpoint
Time to reconsider what Global Burden of Disease studies really tell us about low back pain

Chris Maher, Giovanni Ferreira

doi: 10.1136/annrheumdis-2021-221173
Vasculitis
Novel aspects of regulatory T cell dysfunction as a therapeutic target in giant cell arteritis

Ignatius Ryan Adriawan, Faranaz Atschekzei, Oliver Dittrich-Breiholz, Panagiotis Garantziotis, Stefanie Hirsch, Linus Maximillian Risser, Maike Kosanke, Reinhold Ernst Schmidt, Torsten Witte, Georgios Sogkas

doi: 10.1136/annrheumdis-2021-220955

September 23, 2021

Letter
Temporary hold of mycophenolate augments humoral response to SARS-CoV-2 vaccination in patients with rheumatic and musculoskeletal diseases: a case series
Free

Caoilfhionn M Connolly, Teresa Po-Yu Chiang, Brian J Boyarsky, Jake A Ruddy, Mayan Teles, Jennifer L Alejo, Allan Massie, William A Werbel, Ami A Shah, Lisa Christopher-Stine, Jacqueline Garonzik-Wang, Dorry L Segev, Julie J Paik

doi: 10.1136/annrheumdis-2021-221252
Animal models
Human SLE variant NCF1-R90H promotes kidney damage and murine lupus through enhanced Tfh2 responses induced by defective efferocytosis of macrophages

Linyu Geng, Jian Zhao, Yun Deng, Ivan Molano, Xue Xu, Lingxiao Xu, Phillip Ruiz, Quanzhen Li, Xuebing Feng, Miaojia Zhang, Wenfeng Tan, Diane L Kamen, Sang-Cheol Bae, Gary S Gilkeson, Lingyun Sun, Betty P Tsao

doi: 10.1136/annrheumdis-2021-220793
Letter
B-cell targeted therapy is associated with severe COVID-19 among patients with inflammatory arthritides: a 1-year multicentre study in 1116 successive patients receiving intravenous biologics
Free

Renaud Felten, Pierre-Marie Duret, Elodie Bauer, Nathanael Sedmak, Julien H Djossou, Massiva Bensalem, Marc Ardizzone, Marion Geoffroy, Angelique Fan, Marion Couderc, Jean Hugues Salmon, Laurent Messer, Rose-Marie Javier, Alain Meyer, Emmanuel Chatelus, Christelle Sordet, Luc Pijnenburg, Jérémy Fort, Marina Rinagel, Julia Walther, Cassandre Fabre, Laurent Arnaud, Jean Sibilia, Nicolas Meyer, Francis Berenbaum, isabelle Chary-Valckenaere, Martin Soubrier, Jérémie Sellam, Jacques-Eric Gottenberg

doi: 10.1136/annrheumdis-2021-220549

September 17, 2021

Epidemiology
Native joint infections in Iceland 2003–2017: an increase in postarthroscopic infections

Signý Lea Gunnlaugsdóttir, Helga Erlendsdóttir, Kristján Orri Helgason, Árni Jón Geirsson, Valtýr Thors, Sigurður Guðmundsson, Magnús Gottfreðsson

doi: 10.1136/annrheumdis-2021-220820

September 14, 2021

Viewpoint
From sequential to combination and personalised therapy in lupus nephritis: moving towards a paradigm shift?

Ioannis Parodis, Frederic A Houssiau

doi: 10.1136/annrheumdis-2021-221270

September 11, 2021

Correspondence
Correspondence on “European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance” by Aringer et al
Free

Xavier Bossuyt, Walter Fierz, Pier Luigi Meroni

doi: 10.1136/annrheumdis-2021-221288
Letter
Impact of sustaining SDAI remission for preventing incident of bone fragility fracture in patient with rheumatoid arthritis

Ichiro Yoshii, Naoya Sawada, Tatsumi Chijiwa, Shohei Kokei

doi: 10.1136/annrheumdis-2021-221093
Correspondence response
Response to: Correspondence on “European League Against Rheumatism (EULAR)/American College of Rheumatology (ACR) SLE classification criteria item performance” by Aringer et al
Free

Martin Aringer, Karen Costenbader, Nicolai Leuchten, Thomas Dörner, Sindhu R Johnson

doi: 10.1136/annrheumdis-2021-221374

September 07, 2021

Treatment
Analysing cord blood levels of TNF inhibitors to validate the EULAR points to consider for TNF inhibitor use during pregnancy

Nafise Ghalandari, Erik Kemper, Ineke (Hubertina) Crijns, Gertjan Wolbink, Theo Rispens, Hieronymus TW Smeele, Radboud JEM Dolhain

doi: 10.1136/annrheumdis-2021-221036
Letter
Booster-dose SARS-CoV-2 vaccination in patients with autoimmune disease: a case series
Free

Caoilfhionn M Connolly, Mayan Teles, Sarah Frey, Brian J Boyarsky, Jennifer L Alejo, William A Werbel, Jemima Albayda, Lisa Christopher-Stine, Jacqueline Garonzik-Wang, Dorry L Segev, Julie J Paik

doi: 10.1136/annrheumdis-2021-221206

September 06, 2021

Letter
Clinical characteristics and outcomes of COVID-19 breakthrough infections among vaccinated patients with systemic autoimmune rheumatic diseases
Free

Claire Cook, Naomi J Patel, Kristin M. D’Silva, Tiffany Y -T Hsu, Michael DiIorio, Lauren Prisco, Lily W Martin, Kathleen Vanni, Alessandra Zaccardelli, Derrick Todd, Jeffrey A Sparks, Zachary Scott Wallace

doi: 10.1136/annrheumdis-2021-221326
Letter
SARS-CoV-2 infection after vaccination in patients with inflammatory rheumatic and musculoskeletal diseases
Free

Saskia Lawson-Tovey, Kimme L Hyrich, Laure Gossec, Anja Strangfeld, Loreto Carmona, Bernd Raffeiner, Gözde Kübra Yardımcı, Ludovic Trefond, Nicolas Roux, Ana Rodrigues, Charalampos Papagoras, Elsa F Mateus, Xavier Mariette, Pedro M Machado

doi: 10.1136/annrheumdis-2021-221217

August 30, 2021

Rheumatoid arthritis
Joint inflammation tends to recur in the same joints during the rheumatoid arthritis disease course

Sascha L Heckert, Sytske Anne Bergstra, Xanthe M E Matthijssen, Yvonne P M Goekoop-Ruiterman, Faouzia Fodili, Saskia ten Wolde, Cornelia F Allaart, Tom W J Huizinga

doi: 10.1136/annrheumdis-2021-220882
Rheumatoid arthritis
Olokizumab, a monoclonal antibody against interleukin 6, in combination with methotrexate in patients with rheumatoid arthritis inadequately controlled by methotrexate: efficacy and safety results of a randomised controlled phase III study

Evgeniy Nasonov, Saeed Fatenejad, Eugen Feist, Mariana Ivanova, Elena Korneva, Diana G Krechikova, Aleksey L Maslyanskiy, Mikhail Samsonov, Rumen Stoilov, Elena V Zonova, Mark Genovese

doi: 10.1136/annrheumdis-2021-219876

August 23, 2021

Systemic Lupus erythematosus
Metagenome-wide association study revealed disease-specific landscape of the gut microbiome of systemic lupus erythematosus in Japanese

Yoshihiko Tomofuji, Yuichi Maeda, Eri Oguro-Igashira, Toshihiro Kishikawa, Kenichi Yamamoto, Kyuto Sonehara, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Mayu Yagita, Takuro Nii, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

doi: 10.1136/annrheumdis-2021-220687
Correspondence
Correspondence on “Associations of baseline use of biologic or targeted synthetic DMARDs with COVID-19 severity in rheumatoid arthritis: results from the COVID-19 Global Rheumatology Alliance physician registry” by Sparks et al
Free

Elisa Gremese, Gianfranco Ferraccioli

doi: 10.1136/annrheumdis-2021-220932

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