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  • Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire

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Rheumatoid arthritis
Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire

Authors

  • Sabrina Pollastro Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands Department of Experimental Immunology | Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Paul L Klarenbeek Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Marieke E Doorenspleet Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Barbera D C van Schaik Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Rebecca E E Esveldt Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Rogier M Thurlings Department of Rheumatology, Radboud University Medical Center, Nijmegen, The Netherlands PubMed articlesGoogle scholar articles
  • Maria J H Boumans Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Danielle M Gerlag Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands Clinical Unit Cambridge, GlaxoSmithKline, Cambridge, UK PubMed articlesGoogle scholar articles
  • Paul P Tak Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands Department of Medicine, Cambridge University, Cambridge, Massachusetts, USA Department of Rheumatology, Ghent University, Ghent, Belgium Flagship Pioneering, Cambridge, Massachusetts, USA PubMed articlesGoogle scholar articles
  • Koen Vos Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Frank Baas Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands Laboratory for Diagnostic Genome Analysis, Leiden University Medical Center, Leiden, The Netherlands PubMed articlesGoogle scholar articles
  • Antoine H C van Kampen Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Amsterdam Public Health Research Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  • Niek de Vries Amsterdam Rheumatology and Immunology Center (ARC) | Department of Clinical Immunology and Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands Department of Experimental Immunology | Amsterdam Infection & Immunity Institute, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam, The Netherlands PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Niek de Vries, Amsterdam Rheumatology and Immunology Centre (ARC) | Department of Clinical Immunology & Rheumatology, Amsterdam UMC, location AMC, University of Amsterdam, Amsterdam 1105 AZ, The Netherlands; n.devries{at}amc.uva.nl
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Citation

Pollastro S, Klarenbeek PL, Doorenspleet ME, et al
Non-response to rituximab therapy in rheumatoid arthritis is associated with incomplete disruption of the B cell receptor repertoire
Annals of the Rheumatic Diseases 2019;78:1339-1345.

Publication history

  • Received December 12, 2018
  • Revised May 20, 2019
  • Accepted May 21, 2019
  • First published June 19, 2019.
Online issue publication 
May 12, 2021

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© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made. See: https://creativecommons.org/licenses/by/4.0/.