Does paracetamol (acetaminophen) reduce the pain of osteoarthritis?: a meta-analysis of randomised controlled trials

W Zhang; A Jones; M Doherty

doi:10.1136/ard.2003.018531

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Does paracetamol (acetaminophen) reduce the pain of osteoarthritis?: a meta-analysis of randomised controlled trials

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	Abstract	Full	Pdf
Mar 2004	61	0	58
Apr 2004	78	0	81
May 2004	79	0	59
Jun 2004	67	1	43
Jul 2004	394	520	274
Aug 2004	368	342	227
Sep 2004	198	139	85
Oct 2004	128	160	85
Nov 2004	103	181	73
Dec 2004	167	93	67
Jan 2005	201	186	36
Feb 2005	138	143	42
Mar 2005	144	147	53
Apr 2005	67	117	70
May 2005	60	91	45
Jun 2005	59	72	33
Jul 2005	50	87	57
Aug 2005	50	116	83
Sep 2005	67	170	112
Oct 2005	55	129	92
Nov 2005	49	105	62
Dec 2005	33	85	52
Jan 2006	61	109	54
Feb 2006	34	99	64
Mar 2006	48	111	89
Apr 2006	39	80	83
May 2006	80	99	59
Jun 2006	58	46	33
Jul 2006	87	103	62
Aug 2006	67	66	44
Sep 2006	61	89	50
Oct 2006	80	74	84
Nov 2006	69	61	73
Dec 2006	41	57	44
Jan 2007	53	81	56
Feb 2007	46	83	75
Mar 2007	73	71	61
Apr 2007	76	26	35
May 2007	62	31	25
Jun 2007	85	31	28
Jul 2007	62	40	37
Aug 2007	69	23	19
Sep 2007	76	20	26
Oct 2007	78	20	33
Nov 2007	87	23	32
Dec 2007	54	12	24
Jan 2008	59	19	19
Feb 2008	63	23	18
Mar 2008	74	20	29
Apr 2008	82	31	26
May 2008	80	11	21
Jun 2008	69	14	18
Jul 2008	68	9	27
Aug 2008	75	13	14
Sep 2008	99	16	23
Oct 2008	106	23	24
Nov 2008	94	10	24
Dec 2008	84	15	20
Jan 2009	66	8	22
Feb 2009	67	13	19
Mar 2009	99	13	20
Apr 2009	80	24	32
May 2009	92	12	27
Jun 2009	64	13	22
Jul 2009	59	9	12
Aug 2009	67	6	23
Sep 2009	77	15	28
Oct 2009	71	22	18
Nov 2009	80	8	25
Dec 2009	67	6	15
Jan 2010	52	25	38
Feb 2010	74	10	27
Mar 2010	80	15	24
Apr 2010	71	23	18
May 2010	96	17	15
Jun 2010	80	19	30
Jul 2010	47	12	22
Aug 2010	82	17	14
Sep 2010	83	14	11
Oct 2010	74	13	17
Nov 2010	57	5	12
Dec 2010	71	6	7
Jan 2011	63	11	11
Feb 2011	63	10	16
Mar 2011	83	8	15
Apr 2011	76	7	9
May 2011	59	4	11
Jun 2011	63	10	8
Jul 2011	66	6	16
Aug 2011	64	6	9
Sep 2011	94	9	15
Oct 2011	73	15	22
Nov 2011	83	15	23
Dec 2011	79	37	38
Jan 2012	80	48	48
Feb 2012	48	25	20
Mar 2012	87	36	60
Apr 2012	70	52	42
May 2012	94	66	55
Jun 2012	99	41	55
Jul 2012	57	37	48
Aug 2012	59	40	51
Sep 2012	56	40	47
Oct 2012	97	63	75
Nov 2012	89	54	60
Dec 2012	72	44	50
Jan 2013	105	62	67
Feb 2013	92	61	79
Mar 2013	114	101	96
Apr 2013	129	65	54
May 2013	125	82	72
Jun 2013	65	34	35
Jul 2013	53	121	39
Aug 2013	72	109	73
Sep 2013	98	89	38
Oct 2013	98	68	110
Nov 2013	71	41	45
Dec 2013	72	60	31
Jan 2014	52	59	34
Feb 2014	55	69	21
Mar 2014	89	89	49
Apr 2014	86	94	41
May 2014	104	82	38
Jun 2014	59	47	50
Jul 2014	79	58	38
Aug 2014	52	82	42
Sep 2014	94	114	36
Oct 2014	129	128	52
Nov 2014	114	133	43
Dec 2014	74	126	18
Jan 2015	109	120	30
Feb 2015	121	126	46
Mar 2015	433	165	50
Apr 2015	238	149	51
May 2015	123	104	34
Jun 2015	101	57	24
Jul 2015	94	91	28
Aug 2015	89	157	29
Sep 2015	141	102	37
Oct 2015	85	69	18
Nov 2015	87	93	30
Dec 2015	148	108	31
Jan 2016	135	82	58
Feb 2016	110	93	56
Mar 2016	141	89	43
Apr 2016	125	78	73
May 2016	145	92	38
Jun 2016	111	54	19
Jul 2016	63	37	37
Aug 2016	85	60	33
Sep 2016	87	60	50
Oct 2016	127	72	52
Nov 2016	121	58	40
Dec 2016	120	61	22
Jan 2017	137	55	30
Feb 2017	133	34	25
Mar 2017	114	555	28
Apr 2017	82	2194	19
May 2017	114	4009	46
Jun 2017	2006	5333	24
Jul 2017	8413	8327	45
Aug 2017	5831	5664	33
Sep 2017	5446	5271	36
Oct 2017	5487	5323	32
Nov 2017	6506	6366	28
Dec 2017	2860	2714	26
Jan 2018	718	548	35
Feb 2018	2425	2158	38
Mar 2018	2716	2496	28
Apr 2018	3365	3199	37
May 2018	3218	2998	35
Jun 2018	2759	2646	23
Jul 2018	1702	1582	31
Aug 2018	749	637	28
Sep 2018	1442	1302	36
Oct 2018	857	709	34
Nov 2018	1813	1700	25
Dec 2018	845	693	47
Jan 2019	1136	1013	45
Feb 2019	964	860	27
Mar 2019	921	799	55
Apr 2019	703	573	40
May 2019	1017	734	96
Jun 2019	741	648	29
Jul 2019	865	764	42
Aug 2019	1531	1434	20
Sep 2019	671	579	22
Oct 2019	759	625	43
Nov 2019	713	610	43
Dec 2019	661	559	30
Jan 2020	744	632	22
Feb 2020	648	527	26
Mar 2020	487	392	37
Apr 2020	492	372	42
May 2020	329	221	27
Jun 2020	272	183	25
Jul 2020	305	226	42
Aug 2020	346	242	47
Sep 2020	370	258	36
Oct 2020	437	303	39
Nov 2020	429	313	56
Dec 2020	416	310	27
Jan 2021	407	329	55
Feb 2021	420	326	65
Mar 2021	552	428	141
Apr 2021	569	474	102
May 2021	581	535	110
Jun 2021	361	361	119
Jul 2021	404	395	94
Aug 2021	441	430	38
Sep 2021	409	399	25
Oct 2021	495	391	64
Nov 2021	491	383	59
Dec 2021	491	449	14
Jan 2022	552	411	31
Feb 2022	650	505	34
Mar 2022	1006	848	49
Apr 2022	913	744	47
May 2022	919	729	52
Jun 2022	652	488	47
Jul 2022	771	588	32
Aug 2022	805	662	32
Sep 2022	1048	862	43
Oct 2022	1079	911	37
Nov 2022	927	774	26
Dec 2022	547	405	19
Jan 2023	864	686	28
Feb 2023	949	783	35
Mar 2023	1081	899	42
Apr 2023	830	659	34
May 2023	1095	884	56
Jun 2023	892	716	33
Jul 2023	951	766	55
Aug 2023	786	627	32
Sep 2023	873	719	17
Oct 2023	874	709	28
Nov 2023	733	579	30
Dec 2023	1076	117	14
Jan 2024	344	32	20
Feb 2024	468	16	3
Mar 2024	729	17	8
Apr 2024	677	13	7
May 2024	496	10	2
Jun 2024	476	9	8
Jul 2024	775	22	16
Aug 2024	598	8	12
Sep 2024	899	24	15
Total	121516	110515	10191

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