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Early referral recommendations for ankylosing spondylitis (including pre-radiographic and radiographic forms) in primary care
  1. J Sieper,
  2. M Rudwaleit
  1. Medical Department I, Rheumatology, Campus Benjamin Franklin Charitè, University Medicine Berlin, Germany
  1. Correspondence to:
    Medical Department I
    Rheumatology, Charitè, University Medicine Berlin, Germany, Hindenburgdamm 30, 12200 Berlin, Germany; joachim.siepercharite.de

Abstract

An earlier diagnosis of ankylosing spondylitis (AS) is required because there is still a 5–7 year delay between first symptoms and diagnosis, and new effective treatments are available for active disease. Primary care physicians need easy to apply parameters to help them identify patients with suspected AS for onward referral. The best measures found were inflammatory back pain and HLA-B27 positivity.

  • AS, ankylosing spondylitis
  • CRP, C reactive protein
  • ESR, erythrocyte sedimentation rate
  • IBP, inflammatory back pain
  • LR, likelihood ratio
  • MRI, magnetic resonance imaging
  • NSAIDs, non-steroidal anti-inflammatory drugs
  • ankylosing spondylitis
  • screening
  • primary care

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