Spondyloarthritis

Efficacy and safety of brodalumab, an anti-IL17RA monoclonal antibody, in patients with axial spondyloarthritis: 16-week results from a randomised, placebo-controlled, phase 3 trial

James Cheng-Chung Wei, Tae-Hwan Kim, Mitsumasa Kishimoto, Naoki Ogusu, Haeyoun Jeong, Shigeto Kobayashi, 4827-006 study group, Kurisu Tada, Mitsumasa Kishimoto, Kou Katayama, Atsuo Taniguchi, Yohei Seto, Mitsuhiro Morita, Kazuhiro Hatta, Tetsuya Tomita, Nobuo Negoro, Hitoshi Goto, Shigeyoshi Tsuji, Norikazu Murata, Kiyoshi Matsui, Masahiro Yamamura, Hiroaki Dobashi, Junichi Fukushi, Satoshi Ikemura, Akira Maeyama, Mitsuyo Kinjo, Yukitaka Ueki, Eishi Uechi, Tatsuya Atsumi, Hideto Kameda, Yoshinori Taniguchi, Sei Muraoka, Masanobu Oishi, Seung Jae Hong, Won Park, Shin Seok Lee, Chang Hee Suh, Seong Wook Kang, Tae-Hwan Kim, Jung Yoon Choe, Ji Hyeon Ju, Jin Kyun Park, Seung-Geun Lee, Yun Jong Lee, Sang-Heon Lee, Cheng Chung Wei, Tien Tsai Cheng, Wen Chan Tsai, Chung Ming Huang, Hsin Hua Chen, Der-Yuan Chen, Meng Yu Weng, Shue Fen Luo, Kun Hung Chen, Ling Jung Yen, Cheng Han Wu, Hsiang Cheng Chen

10.1136/annrheumdis-2020-219406

April 7, 2021

Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo

Silvia Menegatti, Vincent Guillemot, Eleonora Latis, Hanane Yahia-Cherbal, Daniela Mittermüller, Vincent Rouilly, Elena Mascia, Nicolas Rosine, Surya Koturan, Gael A Millot, Claire Leloup, Darragh Duffy, Aude Gleizes, Salima Hacein-Bey-Abina, Milieu Intérieur Consortium, Jérémie Sellam, Francis Berenbaum, Corinne Miceli-Richard, Maxime Dougados, Elisabetta Bianchi, Lars Rogge, Milieu Intérieur Consortium, Laurent Abel, Andres Alcover, Hugues Aschard, Kalla Astrom, Philippe Bousso, Pierre Bruhns, Ana Cumano, Caroline Demangel, Ludovic Deriano, James Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo Gomperts-Boneca, Milena Hasan, Serge Hercberg, Olivier Lantz, Hugo Mouquet, Etienne Patin, Sandra Pellegrini, Stanislas Pol, Antonio Rausell, Lars Rogge, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Trouvier, Marie-Noëlle Ungeheuer, Darragh Duffy, Matthew L Albert, Lluis Quintana-Murci

10.1136/annrheumdis-2020-218304

December 2, 2020

Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression

Abdulla Watad, Hannah Rowe, Tobias Russell, Qiao Zhou, Lisa K Anderson, Almas Khan, Robert Dunsmuir, Peter Loughenbury, Vishal Borse, Abhay Rao, Peter A Millner, Nicola Luigi Bragazzi, Howard Amital, Richard Cuhtbert, Miriam Wittmann, Kassem Sharif, Tony Kenna, Matthew A Brown, Darren Newton, Charlie Bridgewood, Dennis G McGonagle

10.1136/annrheumdis-2020-217309

May 13, 2020