Spondyloarthritis

Continuing versus withdrawing ixekizumab treatment in patients with axial spondyloarthritis who achieved remission: efficacy and safety results from a placebo-controlled, randomised withdrawal study (COAST-Y)

Robert BM Landewé, Lianne S Gensler, Denis Poddubnyy, Proton Rahman, Maja Hojnik, Xiaoqi Li, Soyi Liu Leage, David Adams, Hilde Carlier, Filip Van den Bosch, on behalf of the COAST-Y study group, Federico Javier Ariel, Alberto Berman, Judith Carrio, Eleonora Del Valle Lucero, Jose Maldonado Cocco, Benito Jorge Velasco, Heinrich Resch, Johannes Grisar, Valderilio Azevedo, Mauro Keiserman, Flora Marcolino, Ricardo Xavier, Antonio Ximenes, Ana Melazzi, Antonio Scotton, Louis Bessette, Walter Maksymowych, Frederic Morin, Eva Dokoupilova, Zdenek Dvorak, Vlastimil Racek, Radka Moravcova, Martina Malcova, Karel Pavelka, Kari K. Eklund, Pentti Jarvinen, Leena Paimela, Philippe Goupille, Eric Lespessailles, Bernard Combe, Gunther Neeck, Jürgen Braun, Andrea Everding, Regina Cseuz, Edit Drescher, Yolanda Braun Moscovici, Ori Elkayam, Yair Molad, Tatiana Reitblat, Carlo Salvarani, Tetsuya Tomita, Yoshinori Taniguchi, Hiromichi Tamaki, Tokutaro Tsuda, Kurisu Tada, Hiroaki Dobashi, Tadashi Okano, Kentaro Inui, Yukitaka Ueki, Yoshifuji Matsumoto, Yoshinobu Koyama, Tatsuya Atsumi, Hitoshi Goto, Yuya Takakubo, Yeon-Ah Lee, Ji Hyeon Ju, Seong Wook Kang, Tae-Hwan Kim, Chang Keun Lee, Eun Bong Lee, Sang Heon Lee, Min-Chan Park, Kichul Shin, Sang-Hoon Lee, Aaron Alejandro Barrera Rodriguez, Fidencio Cons-Molina, Sergio Duran Barragan, Cassandra Michelle Skinner, Cesar Francisco Pacheco Tena, Cesar Ricardo Ramos Remus, Juan Cruz Rizo Rodriguez, Marleen G. van de Sande, Eduard Griep, Malgorzata Szymanska, Tomasz Blicharski, Jan Brzezicki, Anna Dudek, Pawel Hrycaj, Rafal Plebanski, Artur Racewicz, Rafal Wojciechowski, Marek Krogulec, Daniela Opris-Belinski, Ana Maria Ramazan, Galina Matsievskaya, Evgeniya Schmidt, Tatiana Dubinina, Marina Stanislav, Sergey Yakushin, Olga Ershova, Andrey Rebrov, Carlos Gonzalez Fernandez, Jordi Gratacos Masmitja, Juan Sanchez Burson, Hung-An Chen, Ying-Chou Chen, Song-Chou Hsieh, Joung-Liang Lan, Cheng-Chung Wei, Nicholas Barkham, Karl Gaffney, Sophia Khan, Jonathan Packham, Pippa Watson, Melvin Churchill, Atulya Deodhar, Kathleen Flint, Norman Gaylis, Maria Greenwald, Mary Howell, Akgun Ince, Yoel Drucker, Jeffery L. Kaine, Alan Kivitz, Steven Klein, Clarence Legerton, Daksha Mehta, Eric Mueller, Eric Peters, Roel N. Querubin, John Reveille, Michael Sayers, Craig Scoville, Joseph Shanahan, Richard Roseff, Mark Harris, Roger Diegel, Christine Thai, Gregorio Cortes-Maisonet, Oscar Soto-Raices, Carlos Pantojas

10.1136/annrheumdis-2020-219717

May 6, 2021

Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial

Anna Molto, Clementina López-Medina, Filip E Van den Bosch, Annelies Boonen, Casper Webers, Emanuelle Dernis, Floris A van Gaalen, Martin Soubrier, Pascal Claudepierre, Athan Baillet, Mirian Starmans-Kool, Anneke Spoorenberg, Peggy Jacques, Philippe Carron, Rik Joos, Jan Lenaerts, Laure Gossec, Sophie Pouplin, Adeline Ruyssen-Witrand, Laetitia Sparsa, Astrid van Tubergen, Désirée van der Heijde, Maxime Dougados

10.1136/annrheumdis-2020-219585

May 6, 2021

Polygenic Risk Scores have high diagnostic capacity in ankylosing spondylitis

Zhixiu Li, Xin Wu, Paul J Leo, Erika De Guzman, Nurullah Akkoc, Maxime Breban, Gary J Macfarlane, Mahdi Mahmoudi, Helena Marzo-Ortega, Lisa K Anderson, Lawrie Wheeler, Chung-Tei Chou, Andrew A Harrison, Simon Stebbings, Gareth T Jones, So-Young Bang, Geng Wang, Ahmadreza Jamshidi, Elham Farhadi, Jing Song, Li Lin, Mengmeng Li, James Cheng-Chung Wei, Nicholas G Martin, Margaret J Wright, MinJae Lee, Yuqin Wang, Jian Zhan, Jin-San Zhang, Xiaobing Wang, Zi-Bing Jin, Michael H Weisman, Lianne S Gensler, Michael M Ward, Mohammad Hossein Rahbar, Laura Diekman, Tae-Hwan Kim, John D Reveille, Bryan Paul Wordsworth, Huji Xu, Matthew A Brown, TCRI AS Group, Jian Yin, Lei Jiang, Lin Zhou, Ting Li, Qingwen Wang, Tianwang Li, Guanmin Gao, Shengqian Xu, Weiguo Xiao, Hui Shen, Jingguo Zhou, Yuquan You, Dongbao Zhao, Qing Cai, Shengming Dai, Lan He, Ping Zhu, Zhenyu Jiang, Jian Xu, Huaxiang Wu, Lie Dai, Yang Li, Feng Ding, Xiaochun Zhu, Chongyang Liu, Dongyi He, Liyun Zhang, Zhijun Li, Futao Zhao, Hanshi Xu, Niansong Wang, Youlian Wang, Lindi Jiang, Yu Zhang, Jinwei Chen, Fang Cheng, Zhiyi Zhang, Yifang Mei, Liangjing Lv, Lingli Dong, Jing Yang, Yinong Li, Xiaodong Wang, Xiaofeng Li, Hongsheng Sun, Xianming Long, Xiao Zhang, Qinghong Yu, Xiaodan Kong, Yi Zheng, Miaojia Zhang, Yi Tao, Yisha Li, Xinwang Duan, Qianghua Wei, Xiaofei Wang, Jie Han, Rong Mu, Yiping Lin, Jian Zhu, Xiaoyuan Chen

10.1136/annrheumdis-2020-219446

April 20, 2021

Efficacy and safety of brodalumab, an anti-IL17RA monoclonal antibody, in patients with axial spondyloarthritis: 16-week results from a randomised, placebo-controlled, phase 3 trial

James Cheng-Chung Wei, Tae-Hwan Kim, Mitsumasa Kishimoto, Naoki Ogusu, Haeyoun Jeong, Shigeto Kobayashi, 4827-006 study group, Kurisu Tada, Mitsumasa Kishimoto, Kou Katayama, Atsuo Taniguchi, Yohei Seto, Mitsuhiro Morita, Kazuhiro Hatta, Tetsuya Tomita, Nobuo Negoro, Hitoshi Goto, Shigeyoshi Tsuji, Norikazu Murata, Kiyoshi Matsui, Masahiro Yamamura, Hiroaki Dobashi, Junichi Fukushi, Satoshi Ikemura, Akira Maeyama, Mitsuyo Kinjo, Yukitaka Ueki, Eishi Uechi, Tatsuya Atsumi, Hideto Kameda, Yoshinori Taniguchi, Sei Muraoka, Masanobu Oishi, Seung Jae Hong, Won Park, Shin Seok Lee, Chang Hee Suh, Seong Wook Kang, Tae-Hwan Kim, Jung Yoon Choe, Ji Hyeon Ju, Jin Kyun Park, Seung-Geun Lee, Yun Jong Lee, Sang-Heon Lee, Cheng Chung Wei, Tien Tsai Cheng, Wen Chan Tsai, Chung Ming Huang, Hsin Hua Chen, Der-Yuan Chen, Meng Yu Weng, Shue Fen Luo, Kun Hung Chen, Ling Jung Yen, Cheng Han Wu, Hsiang Cheng Chen

10.1136/annrheumdis-2020-219406

April 7, 2021

Immune response profiling of patients with spondyloarthritis reveals signalling networks mediating TNF-blocker function in vivo

Silvia Menegatti, Vincent Guillemot, Eleonora Latis, Hanane Yahia-Cherbal, Daniela Mittermüller, Vincent Rouilly, Elena Mascia, Nicolas Rosine, Surya Koturan, Gael A Millot, Claire Leloup, Darragh Duffy, Aude Gleizes, Salima Hacein-Bey-Abina, Milieu Intérieur Consortium, Jérémie Sellam, Francis Berenbaum, Corinne Miceli-Richard, Maxime Dougados, Elisabetta Bianchi, Lars Rogge, Milieu Intérieur Consortium, Laurent Abel, Andres Alcover, Hugues Aschard, Kalla Astrom, Philippe Bousso, Pierre Bruhns, Ana Cumano, Caroline Demangel, Ludovic Deriano, James Di Santo, Françoise Dromer, Gérard Eberl, Jost Enninga, Jacques Fellay, Ivo Gomperts-Boneca, Milena Hasan, Serge Hercberg, Olivier Lantz, Hugo Mouquet, Etienne Patin, Sandra Pellegrini, Stanislas Pol, Antonio Rausell, Lars Rogge, Anavaj Sakuntabhai, Olivier Schwartz, Benno Schwikowski, Spencer Shorte, Frédéric Tangy, Antoine Toubert, Mathilde Trouvier, Marie-Noëlle Ungeheuer, Darragh Duffy, Matthew L Albert, Lluis Quintana-Murci

10.1136/annrheumdis-2020-218304

December 2, 2020