Osteoarthritis

Intra-articular sprifermin reduces cartilage loss in addition to increasing cartilage gain independent of location in the femorotibial joint: post-hoc analysis of a randomised, placebo-controlled phase II clinical trial

Felix Eckstein, Jeffrey L Kraines, Aida Aydemir, Wolfgang Wirth, Susanne Maschek, Marc C Hochberg

10.1136/annrheumdis-2019-216453

February 25, 2020

Single-cell RNA-seq analysis identifies meniscus progenitors and reveals the progression of meniscus degeneration

Hao Sun, Xingzhao Wen, Hongyi Li, Peihui Wu, Minghui Gu, Xiaoyi Zhao, Ziji Zhang, Shu Hu, Guping Mao, Ruofan Ma, Weiming Liao, Zhiqi Zhang

10.1136/annrheumdis-2019-215926

December 23, 2019

Interleukin 1 receptor antagonist () gene variants predict radiographic severity of knee osteoarthritis and risk of incident disease

Mukundan Attur, Hua Zhou, Johathan Samuels, Svetlana Krasnokutsky, Michelle Yau, Jose U Scher, Michael Doherty, Anthony G Wilson, Jenny Bencardino, Marc Hochberg, Joanne M Jordan, Braxton Mitchell, Virginia B Kraus, Steven B Abramson

10.1136/annrheumdis-2019-216055

December 18, 2019

Knee osteoarthritis risk in non-industrial societies undergoing an energy balance transition: evidence from the indigenous Tarahumara of Mexico

Ian J Wallace, David T Felson, Steven Worthington, Jeffrey Duryea, Margaret Clancy, Piran Aliabadi, Geeta N Eick, J Josh Snodgrass, Aaron L Baggish, Daniel E Lieberman

10.1136/annrheumdis-2019-215886

September 13, 2019

Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: data from the Osteoarthritis Initiative

María Camacho-Encina, Vanesa Balboa-Barreiro, Ignacio Rego-Perez, Florencia Picchi, Jennifer VanDuin, Ji Qiu, Manuel Fuentes, Natividad Oreiro, Joshua LaBaer, Cristina Ruiz-Romero, Francisco J Blanco

10.1136/annrheumdis-2019-215325

August 30, 2019

CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene

Shuying Shen, Yizheng Wu, Junxin Chen, Ziang Xie, Kangmao Huang, Gangliang Wang, Yute Yang, Weiyu Ni, Zhijun Chen, Peihua Shi, Yan Ma, Shunwu Fan

10.1136/annrheumdis-2018-214786

March 28, 2019

Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

Isabell S von Loga, Aadil El-Turabi, Luke Jostins, Jadwiga Miotla-Zarebska, Jennifer Mackay-Alderson, Andris Zeltins, Ida Parisi, Martin F Bachmann, Tonia L Vincent

10.1136/annrheumdis-2018-214489

March 12, 2019

Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis

Lan Zhao, Jian Huang, Yunshan Fan, Jun Li, Tianming You, Shisheng He, Guozhi Xiao, Di Chen

10.1136/annrheumdis-2018-214724

March 6, 2019

Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade

Wenxue Tong, Yelin Zeng, Dick Ho Kiu Chow, Wai Yeung, Jiankun Xu, Yujie Deng, Shihui Chen, Hui Zhao, Xiaoling Zhang, Kevin Kiwai Ho, Ling Qin, Kingston King-lun Mak

10.1136/annrheumdis-2018-214200

February 11, 2019

Critical role for arginase II in osteoarthritis pathogenesis

Wan-Su Choi, Jeong-In Yang, Wihak Kim, Hyo-Eun Kim, Seul-Ki Kim, Yoonkyung Won, Young-Ok Son, Churl-Hong Chun, Jang-Soo Chun

10.1136/annrheumdis-2018-214282

January 4, 2019