Osteoarthritis

Discovery of an autoantibody signature for the early diagnosis of knee osteoarthritis: data from the Osteoarthritis Initiative

María Camacho-Encina, Vanesa Balboa-Barreiro, Ignacio Rego-Perez, Florencia Picchi, Jennifer VanDuin, Ji Qiu, Manuel Fuentes, Natividad Oreiro, Joshua LaBaer, Cristina Ruiz-Romero, Francisco J Blanco

10.1136/annrheumdis-2019-215325

August 30, 2019

CircSERPINE2 protects against osteoarthritis by targeting miR-1271 and ETS-related gene

Shuying Shen, Yizheng Wu, Junxin Chen, Ziang Xie, Kangmao Huang, Gangliang Wang, Yute Yang, Weiyu Ni, Zhijun Chen, Peihua Shi, Yan Ma, Shunwu Fan

10.1136/annrheumdis-2018-214786

March 28, 2019

Active immunisation targeting nerve growth factor attenuates chronic pain behaviour in murine osteoarthritis

Isabell S von Loga, Aadil El-Turabi, Luke Jostins, Jadwiga Miotla-Zarebska, Jennifer Mackay-Alderson, Andris Zeltins, Ida Parisi, Martin F Bachmann, Tonia L Vincent

10.1136/annrheumdis-2018-214489

March 12, 2019

Exploration of CRISPR/Cas9-based gene editing as therapy for osteoarthritis

Lan Zhao, Jian Huang, Yunshan Fan, Jun Li, Tianming You, Shisheng He, Guozhi Xiao, Di Chen

10.1136/annrheumdis-2018-214724

March 6, 2019

Wnt16 attenuates osteoarthritis progression through a PCP/JNK-mTORC1-PTHrP cascade

Wenxue Tong, Yelin Zeng, Dick Ho Kiu Chow, Wai Yeung, Jiankun Xu, Yujie Deng, Shihui Chen, Hui Zhao, Xiaoling Zhang, Kevin Kiwai Ho, Ling Qin, Kingston King-lun Mak

10.1136/annrheumdis-2018-214200

February 11, 2019

Critical role for arginase II in osteoarthritis pathogenesis

Wan-Su Choi, Jeong-In Yang, Wihak Kim, Hyo-Eun Kim, Seul-Ki Kim, Yoonkyung Won, Young-Ok Son, Churl-Hong Chun, Jang-Soo Chun

10.1136/annrheumdis-2018-214282

January 4, 2019

Mitochondrial DNA haplogroups influence the risk of incident knee osteoarthritis in OAI and CHECK cohorts. A meta-analysis and functional study

Mercedes Fernández-Moreno, Angel Soto-Hermida, María E Vázquez-Mosquera, Estefanía Cortés-Pereira, Sara Relaño, Tamara Hermida-Gómez, Sonia Pértega, Natividad Oreiro-Villar, Carlos Fernández-López, Rafael Garesse, Francisco J Blanco, Ignacio Rego-Pérez

10.1136/annrheumdis-2016-210131

December 5, 2016

Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model

Timothy P LaBranche, Alison M Bendele, Brian C Omura, Kathryn E Gropp, Susan I Hurst, Cedo M Bagi, Thomas R Cummings, Lonnie E Grantham II, David L Shelton, Mark A Zorbas

10.1136/annrheumdis-2015-208913

July 5, 2016

Inhibition of BATF/JUN transcriptional activity protects against osteoarthritic cartilage destruction

Jinseol Rhee, Seo-Hee Park, Seul-Ki Kim, Jin-Hong Kim, Chul-Won Ha, Churl-Hong Chun, Jang-Soo Chun

10.1136/annrheumdis-2015-208953

May 4, 2016

WNT16 antagonises excessive canonical WNT activation and protects cartilage in osteoarthritis

Giovanna Nalesso, Bethan Lynne Thomas, Joanna Claire Sherwood, Jing Yu, Olga Addimanda, Suzanne Elizabeth Eldridge, Anne-Sophie Thorup, Leslie Dale, Georg Schett, Jochen Zwerina, Noha Eltawil, Costantino Pitzalis, Francesco Dell'Accio

10.1136/annrheumdis-2015-208577

May 4, 2016