Osteoarthritis

Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify as novel osteoarthritis gene

Cindy Germaine Boer, Michelle S Yau, Sarah J Rice, Rodrigo Coutinho de Almeida, Kathleen Cheung, Unnur Styrkarsdottir, Lorraine Southam, Linda Broer, Jeremy Mark Wilkinson, André G Uitterlinden, Eleftheria Zeggini, David Felson, John Loughlin, Mariel Young, Terence Dante Capellini, Ingrid Meulenbelt, Joyce BJ van Meurs

10.1136/annrheumdis-2020-217834

October 14, 2020

Efficacy of tocilizumab in patients with hand osteoarthritis: double blind, randomised, placebo-controlled, multicentre trial

Pascal Richette, Augustin Latourte, Jérémie Sellam, Daniel Wendling, Muriel Piperno, Philippe Goupille, Yves-Marie Pers, Florent Eymard, Sébastien Ottaviani, Paul Ornetti, René-Marc Flipo, Bruno Fautrel, Olivier Peyr, Jean Pierre Bertola, Eric Vicaut, Xavier Chevalier

10.1136/annrheumdis-2020-218547

October 14, 2020

Identification of the skeletal progenitor cells forming osteophytes in osteoarthritis

Anke J Roelofs, Karolina Kania, Alexandra J Rafipay, Meike Sambale, Stephanie T Kuwahara, Fraser L Collins, Joanna Smeeton, Maxwell A Serowoky, Lynn Rowley, Hui Wang, René Gronewold, Chrysa Kapeni, Simón Méndez-Ferrer, Christopher B Little, John F Bateman, Thomas Pap, Francesca V Mariani, Joanna Sherwood, J Gage Crump, Cosimo De Bari

10.1136/annrheumdis-2020-218350

September 22, 2020

Risk of venous thromboembolism in knee, hip and hand osteoarthritis: a general population-based cohort study

Chao Zeng, Kim Bennell, Zidan Yang, Uyen-Sa D T Nguyen, Na Lu, Jie Wei, Guanghua Lei, Yuqing Zhang

10.1136/annrheumdis-2020-217782

September 16, 2020

TRIM24-RIP3 axis perturbation accelerates osteoarthritis pathogenesis

Jimin Jeon, Hyun-Jin Noh, Hyemi Lee, Han-Hee Park, Yu-Jin Ha, Seok Hee Park, Haeseung Lee, Seok-Jung Kim, Ho Chul Kang, Seong-il Eyun, Siyoung Yang, You-Sun Kim

10.1136/annrheumdis-2020-217904

September 7, 2020

Serum NT/CT SIRT1 ratio reflects early osteoarthritis and chondrosenescence

George Batshon, Jinan Elayyan, Omar Qiq, Eli Reich, Louisa Ben-Aderet, Leonid Kandel, Amir Haze, Jürgen Steinmeyer, Veronique Lefebvre, Hong Zhang, Jennifer Elisseeff, Yves Henrotin, Ali Mobasheri, Mona Dvir-Ginzberg

10.1136/annrheumdis-2020-217072

July 14, 2020

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination

Gangliang Wang, Shuai Chen, Ziang Xie, Shuying Shen, Wenbin Xu, Wenxiang Chen, Xiang Li, Yizheng Wu, Liangping Li, Bin Liu, Xianjun Ding, An Qin, Shunwu Fan

10.1136/annrheumdis-2019-216911

May 14, 2020

Does cartilage loss cause pain in osteoarthritis and if so, how much?

Kathryn Bacon, Michael P LaValley, S Reza Jafarzadeh, David Felson

10.1136/annrheumdis-2020-217363

May 7, 2020

BCP crystals promote chondrocyte hypertrophic differentiation in OA cartilage by sequestering Wnt3a

Jessica Bertrand, Tabea Kräft, Tobias Gronau, Joanna Sherwood, Frank Rutsch, Frédéric Lioté, Francisco Dell'Accio, Christoph H Lohmann, Miriam Bollmann, Annelena Held, Thomas Pap

10.1136/annrheumdis-2019-216648

May 5, 2020

Faecal microbiota transplantation from metabolically compromised human donors accelerates osteoarthritis in mice

ZeYu Huang, Jing Chen, BoLei Li, Benhua Zeng, Ching-Heng Chou, Xin Zheng, JingWei Xie, Hao Li, Yu Hao, Guo Chen, FuXing Pei, Bin Shen, Virginia B Kraus, Hong Wei, Xuedong Zhou, Lei Cheng

10.1136/annrheumdis-2019-216471

March 23, 2020