Meta-analysis of erosive hand osteoarthritis identifies four common variants that associate with relatively large effectUnnur Styrkarsdottir, Lilja Stefansdottir, Gudmar Thorleifsson, Olafur A Stefansson, Saedis Saevarsdottir, Sigrun H Lund, Thorunn Rafnar, Kazuyuki Hoshijima, Kendra Novak, Natividad Oreiro, Ignacio Rego-Perez, Channing Hansen, Nikolas Kazmers, Lambertus A Kiemeney, Francisco J BlancoSee the full list of authors
17 March 2023
Increased risk of osteoarthritis in patients with atopic diseaseMatthew C Baker, Khushboo Sheth, Rong Lu, Di Lu, Ericka P von Kaeppler, Archana Bhat, David T Felson, William H Robinson
27 March 2023
Human-specific duplicate CHRFAM7A gene is associated with more severe osteoarthritis and amplifies pain behavioursAlice Courties, Merissa Olmer, Kevin Myers, Phillip Ordoukhanian, Steven R Head, Padmaja Natarajan, Francis Berenbaum, Jérémie Sellam, Martin K Lotz
10 January 2023
Stage-specific and location-specific cartilage calcification in osteoarthritis developmentXiaozhao Wang, Qin Wu, Ru Zhang, Zhang Fan, Wenyue Li, Renwei Mao, Zihao Du, Xudong Yao, Yuanzhu Ma, Yiyang Yan, Wei Sun, Hongwei Wu, Wei Wei, Yejun Hu, Yi HongSee the full list of authors
19 October 2022
Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacementCecilie Henkel, Unnur Styrkársdóttir, Gudmar Thorleifsson, Lilja Stefánsdóttir, Gyda Björnsdóttir, Karina Banasik, Søren Brunak, Christian Erikstrup, Khoa Manh Dinh, Thomas Folkmann Hansen, Kaspar René Nielsen, Mie Topholm Bruun, Joseph Dowsett, Thorsten Brodersen, DBDS Genomic ConsortiumSee the full list of authors
14 November 2022
Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscusHannah Swahn, Kun Li, Tomas Duffy, Merissa Olmer, Darryl D D'Lima, Tony S Mondala, Padmaja Natarajan, Steven R Head, Martin K Lotz
23 December 2022
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritisAlexander J Knights, Easton C Farrell, Olivia M Ellis, Lindsey Lammlin, Lucas M Junginger, Phillip M Rzeczycki, Rachel F Bergman, Rida Pervez, Monique Cruz, Eleanor Knight, Dennis Farmer, Alexa A Samani, Chia-Lung Wu, Kurt D Hankenson, Tristan Maerz
29 September 2022
Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritisHiroki Ohzono, Yiwen Hu, Keita Nagira, Haruhisa Kanaya, Naoki Okubo, Merissa Olmer, Masafumi Gotoh, Ichiro Kurakazu, Yukio Akasaki, Manabu Kawata, Emily Chen, Alan C Chu, Kristen A Johnson, Martin K Lotz
15 September 2022
NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibilityMichael J Jurynec, Catherine M Gavile, Matthew Honeggar, Ying Ma, Shivakumar R Veerabhadraiah, Kendra A Novak, Kazuyuki Hoshijima, Nikolas H Kazmers, David J Grunwald
22 June 2022
Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritisManabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, Martin K Lotz
9 May 2022
