Early arthritis

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Liang Kuang, Jiangyi Wu, Nan Su, Huabing Qi, Hangang Chen, Siru Zhou, Yan Xiong, Xiaolan Du, Qiaoyan Tan, Jing Yang, Min Jin, Fengtao Luo, Junjie Ouyang, Bin Zhang, Zuqiang Wang, Wanling Jiang, Liang Chen, Shuai Chen, Ziming Wang, Peng Liu, Liangjun Yin, Fengjin Guo, Chuxia Deng, Di Chen, Chuanju Liu, Yangli Xie, Zhenhong Ni, Lin Chen

10.1136/annrheumdis-2019-215696

October 29, 2019

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

Gloria Lliso-Ribera, Frances Humby, Myles Lewis, Alessandra Nerviani, Daniele Mauro, Felice Rivellese, Stephen Kelly, Rebecca Hands, Fabiola Bene, Nandhini Ramamoorthi, Jason A Hackney, Alberto Cauli, Ernest H Choy, Andrew Filer, Peter C Taylor, Iain McInnes, Michael J Townsend, Costantino Pitzalis

10.1136/annrheumdis-2019-215751

October 2, 2019

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

Frances Humby, Myles Lewis, Nandhini Ramamoorthi, Jason A Hackney, Michael R Barnes, Michele Bombardieri, A. Francesca Setiadi, Stephen Kelly, Fabiola Bene, Maria DiCicco, Sudeh Riahi, Vidalba Rocher, Nora Ng, Ilias Lazarou, Rebecca Hands, Désirée van der Heijde, Robert B M Landewé, Annette van der Helm-van Mil, Alberto Cauli, Iain McInnes, Christopher Dominic Buckley, Ernest H Choy, Peter C Taylor, Michael J Townsend, Costantino Pitzalis

10.1136/annrheumdis-2018-214539

March 16, 2019