Autoimmunity

Tfh cells with NLRP3 inflammasome activation are essential for high-affinity antibody generation, germinal centre formation and autoimmunity

Zhenhuan Zhao, Bihua Xu, Shuang Wang, Mianjing Zhou, Yuefang Huang, Chaohuan Guo, Mengyuan Li, Jijun Zhao, Sun-Sang J Sung, Felicia Gaskin, Niansheng Yang, Shu Man Fu

10.1136/annrheumdis-2021-221985

April 12, 2022

Increment of immunogenicity after third dose of a homologous inactivated SARS-CoV-2 vaccine in a large population of patients with autoimmune rheumatic diseases

Nádia Emi Aikawa, Leonard de Vinci Kanda Kupa, Ana Cristina Medeiros-Ribeiro, Carla Goncalves Schahin Saad, Emily Figueiredo Neves Yuki, Sandra Gofinet Pasoto, Priscila Tagliaferro Rojo, Rosa Maria Rodrigues Pereira, Samuel Katsuyuki Shinjo, Percival Degrava Sampaio-Barros, Danieli Castro Oliveira Andrade, Ari Stiel Radu Halpern, Ricardo Fuller, Fernando Henrique Carlos Souza, Lissiane Karine Noronha Guedes, Ana Paula Luppino Assad, Julio Cesar Bertacini de Moraes, Michelle Remiao Ugolini Lopes, Victor Adriano de Oliveira Martins, Lorena Betancourt, Carolina Torres Ribeiro, Lucas Peixoto Sales, Isabela Maria Bertoglio, Virginia Lucia Nazario Bonoldi, Renata Lys Pinheiro Mello, Gustavo Guimaraes Moreira Balbi, Ana Marli Christovam Sartori, Leila Antonangelo, Clóvis Artur Silva, Eloisa Bonfa

10.1136/annrheumdis-2021-222096

March 11, 2022

Average corticosteroid dose and risk for HBV reactivation and hepatitis flare in patients with resolved hepatitis B infection

Zhenyu Zhong, Weiting Liao, Lingyu Dai, Xiaojie Feng, Guannan Su, Yu Gao, Qiuying Wu, Peizeng Yang

10.1136/annrheumdis-2021-221650

December 21, 2021

Whole gut virome analysis of 476 Japanese revealed a link between phage and autoimmune disease

Yoshihiko Tomofuji, Toshihiro Kishikawa, Yuichi Maeda, Kotaro Ogawa, Takuro Nii, Tatsusada Okuno, Eri Oguro-Igashira, Makoto Kinoshita, Kenichi Yamamoto, Kyuto Sonehara, Mayu Yagita, Akiko Hosokawa, Daisuke Motooka, Yuki Matsumoto, Hidetoshi Matsuoka, Maiko Yoshimura, Shiro Ohshima, Shota Nakamura, Hidenori Inohara, Hideki Mochizuki, Kiyoshi Takeda, Atsushi Kumanogoh, Yukinori Okada

10.1136/annrheumdis-2021-221267

December 8, 2021

Rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome shared megakaryocyte expansion in peripheral blood

Yukai Wang, Xuezhen Xie, Chengpeng Zhang, Miaotong Su, Sini Gao, Jing Wang, Changhao Lu, Qisheng Lin, Jianqun Lin, Marco Matucci-Cerinic, Daniel E Furst, Guohong Zhang

10.1136/annrheumdis-2021-220066

August 30, 2021

Anticardiolipin and other antiphospholipid antibodies in critically ill COVID-19 positive and negative patients

Uriel Trahtemberg, Robert Rottapel, Claudia C Dos Santos, Arthur S Slutsky, Andrew Baker, Marvin J Fritzler

10.1136/annrheumdis-2021-220206

April 26, 2021

Arg206Cys substitution in causes a defect in DNASE1L3 protein secretion that confers risk of systemic lupus erythematosus

Latanya N Coke, Hongxiu Wen, Mary Comeau, Mustafa H Ghanem, Andrew Shih, Christine N Metz, Wentian Li, Carl D Langefeld, Peter K Gregersen, Kim R Simpfendorfer

10.1136/annrheumdis-2020-218810

January 17, 2021

Anti-centromere antibodies target centromere–kinetochore macrocomplex: a comprehensive autoantigen profiling

Nobuhiko Kajio, Masaru Takeshita, Katsuya Suzuki, Yukari Kaneda, Humitsugu Yamane, Kazuhiro Ikeura, Hidekazu Sato, Shin Kato, Hiroyuki Shimizu, Kazuyuki Tsunoda, Tsutomu Takeuchi

10.1136/annrheumdis-2020-218881

November 18, 2020

In vitro elimination of autoreactive B cells from rheumatoid arthritis patients by universal chimeric antigen receptor T cells

Bo Zhang, Yan Wang, Yeshuang Yuan, Jiaqi Sun, Lulu Liu, Dan Huang, Jin Hu, Min Wang, Shengjie Li, Wei Song, Hua Chen, Demin Zhou, Xuan Zhang

10.1136/annrheumdis-2020-217844

September 30, 2020

Germline genetic patterns underlying familial rheumatoid arthritis, systemic lupus erythematosus and primary Sjögren’s syndrome highlight T cell-initiated autoimmunity

Yukai Wang, Shaoqi Chen, Jingyao Chen, Xuezhen Xie, Sini Gao, Chengpeng Zhang, Songxia Zhou, Jing Wang, Ruiqin Mai, Qisheng Lin, Jianqun Lin, Marco Matucci-Cerinic, Guohong Zhang, Daniel E Furst

10.1136/annrheumdis-2019-215533

December 17, 2019