Haemodynamic phenotypes and survival in patients with systemic sclerosis: the impact of the new definition of pulmonary arterial hypertensionPanagiota Xanthouli, Suzana Jordan, Nicklas Milde, Alberto Marra, Norbert Blank, Benjamin Egenlauf, Matthias Gorenflo, Satenik Harutyunova, Hanns-Martin Lorenz, Christian Nagel, Vivienne Theobald, Mona Lichtblau, Charlotte Berlier, Silvia Ulrich, Ekkehard GrünigSee the full list of authors
9 December 2019
Global skin gene expression analysis of early diffuse cutaneous systemic sclerosis shows a prominent innate and adaptive inflammatory profileBrian Skaug, Dinesh Khanna, William R Swindell, Monique E Hinchcliff, Tracy M Frech, Virginia D Steen, Faye N Hant, Jessica K Gordon, Ami A Shah, Lisha Zhu, W Jim Zheng, Jeffrey L Browning, Alexander M S Barron, Minghua Wu, Sudha VisvanathanSee the full list of authors
25 November 2019
Revised European Scleroderma Trials and Research Group Activity Index is the best predictor of short-term severity accrualSerena Fasano, Antonella Riccardi, Valentina Messiniti, Paola Caramaschi, Edoardo Rosato, Britta Maurer, Vanessa Smith, Elise Siegert, Ellen De Langhe, Valeria Riccieri, Paolo Airó, Carina Mihai, Jerome Avouac, Elisabetta Zanatta, Ulrich A WalkerSee the full list of authors
17 August 2019
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugsAlexandru-Emil Matei, Chih-Wei Chen, Lisa Kiesewetter, Andrea-Hermina Györfi, Yi-Nan Li, Thuong Trinh-Minh, Xiaohan Xu, Cuong Tran Manh, Toin van Kuppevelt, Jan Hansmann, Astrid Jüngel, Georg Schett, Florian Groeber-Becker, Jörg H W Distler
20 September 2019
Vasodilators and low-dose acetylsalicylic acid are associated with a lower incidence of distinct primary myocardial disease manifestations in systemic sclerosis: results of the DeSScipher inception cohort studyGabriele Valentini, Dörte Huscher, Antonella Riccardi, Serena Fasano, Rosaria Irace, Valentina Messiniti, Marco Matucci-Cerinic, Serena Guiducci, Oliver Distler, Britta Maurer, Jérôme Avouac, Ingo H Tarner, Marc Frerix, Gabriela Riemekasten, Elise SiegertSee the full list of authors
7 August 2019
Interferon regulatory factor 7 (IRF7) represents a link between inflammation and fibrosis in the pathogenesis of systemic sclerosisMinghua Wu, Brian Skaug, Xiongjie Bi, Tingting Mills, Gloria Salazar, Xiaodong Zhou, John Reveille, Sandeep K Agarwal, Michael R Blackburn, Maureen D Mayes, Shervin Assassi
22 August 2019
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signaturesShervin Assassi, Xuan Wang, Guocai Chen, Ellen Goldmuntz, Lynette Keyes-Elstein, Jun Ying, Paul K Wallace, Jacob Turner, W Jim Zheng, Virginia Pascual, John Varga, Monique E Hinchcliff, Chiara Bellocchi, Peter McSweeney, Daniel E FurstSee the full list of authors
7 August 2019
Single-cell analysis reveals fibroblast heterogeneity and myofibroblasts in systemic sclerosis-associated interstitial lung diseaseEleanor Valenzi, Melissa Bulik, Tracy Tabib, Christina Morse, John Sembrat, Humberto Trejo Bittar, Mauricio Rojas, Robert Lafyatis
12 August 2019
Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysisMike Becker, Nicole Graf, Rafael Sauter, Yannick Allanore, John Curram, Christopher P Denton, Dinesh Khanna, Marco Matucci-Cerinic, Janethe de Oliveira Pena, Janet E Pope, Oliver Distler, , EUSTAR Collaborators (numerical order of centres), Marco Matucci-Cerinic, Serena GuiducciSee the full list of authors
21 June 2019
Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosisAdi Mor, Michal Segal Salto, Avi Katav, Neta Barashi, Victoria Edelshtein, Mirko Manetti, Yair Levi, Jacob George, Marco Matucci-Cerinic
25 May 2019