Continued treatment with nintedanib in patients with systemic sclerosis-associated interstitial lung disease: data from SENSCIS-ONYannick Allanore, Madelon C Vonk, Oliver Distler, Arata Azuma, Maureen D Mayes, Martina Gahlemann, Alexandra James, Veronika Kohlbrenner, Margarida Alves, Dinesh Khanna, Kristin B Highland,
16 August 2022
Induced antibodies directed to the angiotensin receptor type 1 provoke skin and lung inflammation, dermal fibrosis and act species overarchingXiaoyang Yue, Junping Yin, Xiaoqing Wang, Harald Heidecke, Alexander Maximilian Hackel, Xiaoru Dong, Brigitte Kasper, Lifang Wen, Liang Zhang, Kai Schulze-Forster, Juliane Junker, Hanna Grasshoff, Antje Müller, Gerd Wallukat, Ingolf SchimkeSee the full list of authors
20 May 2022
Peripheral blood gene expression profiling shows predictive significance for response to mycophenolate in systemic sclerosis-related interstitial lung diseaseShervin Assassi, Elizabeth R Volkmann, W Jim Zheng, Xuan Wang, Holly Wilhalme, Marka A Lyons, Michael D Roth, Donald P Tashkin
21 February 2022
Large-scale analysis of longitudinal skin gene expression in systemic sclerosis reveals relationships of immune cell and fibroblast activity with skin thickness and a trend towards normalisation over timeBrian Skaug, Marka A Lyons, William R Swindell, Gloria A Salazar, Minghua Wu, Tuan M Tran, Julio Charles, Connor P Vershel, Maureen D Mayes, Shervin Assassi
22 December 2021
Development and validation of a patient-reported outcome measure for systemic sclerosis: the EULAR Systemic Sclerosis Impact of Disease (ScleroID) questionnaireMike O Becker, Rucsandra Dobrota, Alexandru Garaiman, Rudolf Debelak, Kim Fligelstone, Ann Tyrrell Kennedy, Annelise Roennow, Yannick Allanore, Patricia E Carreira, László Czirják, Christopher P Denton, Roger Hesselstrand, Gunnel Sandqvist, Otylia Kowal-Bielecka, Cosimo BruniSee the full list of authors
25 November 2021
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosisMaya Malaab, Ludivine Renaud, Naoko Takamura, Kip D Zimmerman, Willian A da Silveira, Paula S Ramos, Sandra Haddad, Marc Peters-Golden, Loka R Penke, Bethany Wolf, Gary Hardiman, Carl D Langefeld, Thomas A Medsger, Carol A Feghali-Bostwick
8 November 2021
Integrative analysis of lung molecular signatures reveals key drivers of systemic sclerosis-associated interstitial lung diseaseSeung Min Jung, Kyung-Su Park, Ki-Jo Kim
11 August 2021
TGFβ promotes low IL10-producing ILC2 with profibrotic ability involved in skin fibrosis in systemic sclerosisPaôline Laurent, Benoit Allard, Pauline Manicki, Valérie Jolivel, Emeline Levionnois, Mohamed Jeljeli, Pauline Henrot, Julien Izotte, Damien Leleu, Alexis Groppi, Julien Seneschal, Joel Constans, Carlo Chizzolini, Christophe Richez, Pierre DuffauSee the full list of authors
20 July 2021
Molecular basis for clinical diversity between autoantibody subsets in diffuse cutaneous systemic sclerosisKristina Elizabeth Neergaard Clark, Corrado Campochiaro, Eszter Csomor, Adam Taylor, Katherine Nevin, Nicholas Galwey, Mary A Morse, Jennifer Singh, Yee Voan Teo, Voon H Ong, Emma Derrett-Smith, Nicolas Wisniacki, Shaun M Flint, Christopher P Denton
6 July 2021
Single-cell transcriptome analysis identifies skin-specific T-cell responses in systemic sclerosisAlyxzandria M Gaydosik, Tracy Tabib, Robyn Domsic, Dinesh Khanna, Robert Lafyatis, Patrizia Fuschiotti
24 May 2021