Stage-specific and location-specific cartilage calcification in osteoarthritis developmentXiaozhao Wang, Qin Wu, Ru Zhang, Zhang Fan, Wenyue Li, Renwei Mao, Zihao Du, Xudong Yao, Yuanzhu Ma, Yiyang Yan, Wei Sun, Hongwei Wu, Wei Wei, Yejun Hu, Yi HongSee the full list of authors
19 October 2022
Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacementCecilie Henkel, Unnur Styrkársdóttir, Gudmar Thorleifsson, Lilja Stefánsdóttir, Gyda Björnsdóttir, Karina Banasik, Søren Brunak, Christian Erikstrup, Khoa Manh Dinh, Thomas Folkmann Hansen, Kaspar René Nielsen, Mie Topholm Bruun, Joseph Dowsett, Thorsten Brodersen, DBDS Genomic ConsortiumSee the full list of authors
14 November 2022
Senescent cell population with ZEB1 transcription factor as its main regulator promotes osteoarthritis in cartilage and meniscusHannah Swahn, Kun Li, Tomas Duffy, Merissa Olmer, Darryl D D'Lima, Tony S Mondala, Padmaja Natarajan, Steven R Head, Martin K Lotz
23 December 2022
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritisAlexander J Knights, Easton C Farrell, Olivia M Ellis, Lindsey Lammlin, Lucas M Junginger, Phillip M Rzeczycki, Rachel F Bergman, Rida Pervez, Monique Cruz, Eleanor Knight, Dennis Farmer, Alexa A Samani, Chia-Lung Wu, Kurt D Hankenson, Tristan Maerz
29 September 2022
Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritisHiroki Ohzono, Yiwen Hu, Keita Nagira, Haruhisa Kanaya, Naoki Okubo, Merissa Olmer, Masafumi Gotoh, Ichiro Kurakazu, Yukio Akasaki, Manabu Kawata, Emily Chen, Alan C Chu, Kristen A Johnson, Martin K Lotz
15 September 2022
NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibilityMichael J Jurynec, Catherine M Gavile, Matthew Honeggar, Ying Ma, Shivakumar R Veerabhadraiah, Kendra A Novak, Kazuyuki Hoshijima, Nikolas H Kazmers, David J Grunwald
22 June 2022
Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritisManabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, Martin K Lotz
9 May 2022
METTL3-mediated mA modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progressionXiang Chen, Wang Gong, Xiaoyan Shao, Tianshu Shi, Lei Zhang, Jian Dong, Yong Shi, Siyu Shen, Jianghui Qin, Qing Jiang, Baosheng Guo
27 October 2021
Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7Haiyan Zhang, Yan Shao, Zihao Yao, Liangliang Liu, Hongbo Zhang, Jianbin Yin, Haoyu Xie, Kai Li, Pinglin Lai, Hua Zeng, Guozhi Xiao, Chun Zeng, Daozhang Cai, Xiaochun Bai
20 January 2022
Osteoarthritis endotype discovery via clustering of biochemical marker dataFederico Angelini, Paweł Widera, Ali Mobasheri, Joseph Blair, André Struglics, Melanie Uebelhoer, Yves Henrotin, Anne CA Marijnissen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Christoph Ladel, Jonathan Larkin, Anne C Bay-JensenSee the full list of authors
4 March 2022