Allogenic bone marrow–derived mesenchymal stromal cell–based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study)Yves-Marie Pers, Robert Soler-Rich, Gianluca Vadalà, Rosanna Ferreira, Claire Duflos, Marie-Christine Picot, Fanchon Herman, Sylvie Broussous, Ana Sánchez, David Noriega, Francisco Ardura, Mercedes Alberca Zaballos, Verónica García, Virginia Gordillo Cano, Margarita González-VallinasSee the full list of authors
11 October 2024
Efficacy, safety and tolerability of GSK3858279, an anti-CCL17 monoclonal antibody and analgesic, in healthy volunteers and patients with knee osteoarthritis pain: a phase I, randomised, double-blind, placebo-controlled, proof-of-mechanism and proof-of-concept studyJagtar Singh Nijjar, Katharine Abbott-Banner, Yolanda Alvarez, Nicola Aston, Damon Bass, Jane H Bentley, Joanne Ellis, Christian Ellson, Edward C Emery, Maria Feeney, Disala Fernando, David Inman, Rejbinder Kaur, Louise K Modis, Sam Munoz VicenteSee the full list of authors
17 October 2024
Cell and transcriptomic diversity of infrapatellar fat pad during knee osteoarthritisHayley Peters, Pratibha Potla, Jason S Rockel, Teodora Tockovska, Chiara Pastrello, Igor Jurisica, Keemo Delos Santos, Shabana Vohra, Noah Fine, Starlee Lively, Kim Perry, Nikita Looby, Sheng Han Li, Vinod Chandran, Katrina HuenikenSee the full list of authors
7 October 2024
Comparison of definitions of early knee osteoarthritis for likelihood of progression at 2-year and 5-year follow-up: the Multicenter Osteoarthritis StudyJean W Liew, Eva Petrow, Sarah Tilley, Michael P LaValley, Frank W Roemer, Ali Guermazi, Cora E Lewis, James Torner, Michael C Nevitt, John A Lynch, David Felson
3 October 2024
Predicting rapid progression in knee osteoarthritis: a novel and interpretable automated machine learning approach, with specific focus on young patients and early diseaseSimone Castagno, Mark Birch, Mihaela van der Schaar, Andrew McCaskie
4 September 2024
SerpinA3N limits cartilage destruction in osteoarthritis by inhibiting macrophage-derived leucocyte elastaseAugustin Latourte, Sarah Jaulerry, Alice Combier, Chahrazad Cherifi, Yohan Jouan, Thierry Grange, Julien Daligault, Hang-Korng Ea, Martine Cohen-Solal, Eric Hay, Pascal Richette
12 August 2024
Primary osteoarthritis chondrocyte map of chromatin conformation reveals novel candidate effector genesNorbert Bittner, Chenfu Shi, Danyun Zhao, James Ding, Lorraine Southam, Diane Swift, Peter Kreitmaier, Mauro Tutino, Odysseas Stergiou, Jackson T S Cheung, Georgia Katsoula, Jenny Hankinson, Jeremy Mark Wilkinson, Gisela Orozco, Eleftheria Zeggini
13 March 2024
Unveiling inflammatory and prehypertrophic cell populations as key contributors to knee cartilage degeneration in osteoarthritis using multi-omics data integrationYue Fan, Xuzhao Bian, Xiaogao Meng, Lei Li, Laiyi Fu, Yanan Zhang, Long Wang, Yan Zhang, Dalong Gao, Xiong Guo, Mikko Juhani Lammi, Guangdun Peng, Shiquan Sun
7 February 2024
Global burden of early-onset osteoarthritis, 1990–2019: results from the Global Burden of Disease Study 2019Qianlin Weng, Qiu Chen, Ting Jiang, Yuqing Zhang, Weiya Zhang, Michael Doherty, Junqing Xie, Ke Liu, Jiatian Li, Tuo Yang, Jie Wei, Guanghua Lei, Chao Zeng
1 March 2024
Erosive hand osteoarthritis and sarcopenia: data from Osteoarthritis Initiative cohortKamyar Moradi, Robert M Kwee, Bahram Mohajer, Ali Guermazi, Frank W Roemer, Hamza Ahmed Ibad, Ida K Haugen, Francis Berenbaum, Shadpour Demehri
19 January 2024