Genome-wide association meta-analysis of knee and hip osteoarthritis uncovers genetic differences between patients treated with joint replacement and patients without joint replacementCecilie Henkel, Unnur Styrkársdóttir, Gudmar Thorleifsson, Lilja Stefánsdóttir, Gyda Björnsdóttir, Karina Banasik, Søren Brunak, Christian Erikstrup, Khoa Manh Dinh, Thomas Folkmann Hansen, Kaspar René Nielsen, Mie Topholm Bruun, Joseph Dowsett, Thorsten Brodersen, DBDS Genomic Consortium
See the full list of authors14 November 2022
Stage-specific and location-specific cartilage calcification in osteoarthritis developmentXiaozhao Wang, Qin Wu, Ru Zhang, Zhang Fan, Wenyue Li, Renwei Mao, Zihao Du, Xudong Yao, Yuanzhu Ma, Yiyang Yan, Wei Sun, Hongwei Wu, Wei Wei, Yejun Hu, Yi Hong
See the full list of authors19 October 2022
Synovial fibroblasts assume distinct functional identities and secrete R-spondin 2 in osteoarthritisAlexander J Knights, Easton C Farrell, Olivia M Ellis, Lindsey Lammlin, Lucas M Junginger, Phillip M Rzeczycki, Rachel F Bergman, Rida Pervez, Monique Cruz, Eleanor Knight, Dennis Farmer, Alexa A Samani, Chia-Lung Wu, Kurt D Hankenson, Tristan Maerz
23 January 2023
Targeting FoxO transcription factors with HDAC inhibitors for the treatment of osteoarthritisHiroki Ohzono, Yiwen Hu, Keita Nagira, Haruhisa Kanaya, Naoki Okubo, Merissa Olmer, Masafumi Gotoh, Ichiro Kurakazu, Yukio Akasaki, Manabu Kawata, Emily Chen, Alan C Chu, Kristen A Johnson, Martin K Lotz
23 January 2023
NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibilityMichael J Jurynec, Catherine M Gavile, Matthew Honeggar, Ying Ma, Shivakumar R Veerabhadraiah, Kendra A Novak, Kazuyuki Hoshijima, Nikolas H Kazmers, David J Grunwald
12 September 2022
Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritisManabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, Martin K Lotz
12 July 2022
METTL3-mediated mA modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progressionXiang Chen, Wang Gong, Xiaoyan Shao, Tianshu Shi, Lei Zhang, Jian Dong, Yong Shi, Siyu Shen, Jianghui Qin, Qing Jiang, Baosheng Guo
2 May 2022
Osteoarthritis endotype discovery via clustering of biochemical marker dataFederico Angelini, Paweł Widera, Ali Mobasheri, Joseph Blair, André Struglics, Melanie Uebelhoer, Yves Henrotin, Anne CA Marijnissen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Christoph Ladel, Jonathan Larkin, Anne C Bay-Jensen
See the full list of authors8 April 2022
Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7Haiyan Zhang, Yan Shao, Zihao Yao, Liangliang Liu, Hongbo Zhang, Jianbin Yin, Haoyu Xie, Kai Li, Pinglin Lai, Hua Zeng, Guozhi Xiao, Chun Zeng, Daozhang Cai, Xiaochun Bai
8 April 2022
Exercise and education versus saline injections for knee osteoarthritis: a randomised controlled equivalence trialElisabeth Bandak, Robin Christensen, Anders Overgaard, Lars Erik Kristensen, Karen Ellegaard, Jørgen Guldberg-Møller, Cecilie Bartholdy, David J Hunter, Roy Altman, Henning Bliddal, Marius Henriksen
10 March 2022
