Krüppel-like factor-4 and Krüppel-like factor-2 are important regulators of joint tissue cells and protect against tissue destruction and inflammation in osteoarthritisManabu Kawata, Takeshi Teramura, Philip Ordoukhanian, Steven R Head, Padmaja Natarajan, Aishwarya Sundaresan, Merissa Olmer, Hiroshi Asahara, Martin K Lotz
9 May 2022
NOD/RIPK2 signalling pathway contributes to osteoarthritis susceptibilityMichael J Jurynec, Catherine M Gavile, Matthew Honeggar, Ying Ma, Shivakumar R Veerabhadraiah, Kendra A Novak, Kazuyuki Hoshijima, Nikolas H Kazmers, David J Grunwald
22 June 2022
METTL3-mediated mA modification of ATG7 regulates autophagy-GATA4 axis to promote cellular senescence and osteoarthritis progressionXiang Chen, Wang Gong, Xiaoyan Shao, Tianshu Shi, Lei Zhang, Jian Dong, Yong Shi, Siyu Shen, Jianghui Qin, Qing Jiang, Baosheng Guo
27 October 2021
Osteoarthritis endotype discovery via clustering of biochemical marker dataFederico Angelini, Paweł Widera, Ali Mobasheri, Joseph Blair, André Struglics, Melanie Uebelhoer, Yves Henrotin, Anne CA Marijnissen, Margreet Kloppenburg, Francisco J Blanco, Ida K Haugen, Francis Berenbaum, Christoph Ladel, Jonathan Larkin, Anne C Bay-Jensen
See the full list of authors4 March 2022
Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7Haiyan Zhang, Yan Shao, Zihao Yao, Liangliang Liu, Hongbo Zhang, Jianbin Yin, Haoyu Xie, Kai Li, Pinglin Lai, Hua Zeng, Guozhi Xiao, Chun Zeng, Daozhang Cai, Xiaochun Bai
20 January 2022
Digoxin targets low density lipoprotein receptor-related protein 4 and protects against osteoarthritisKai-di Wang, Xiang Ding, Nan Jiang, Chao Zeng, Jing Wu, Xian-yi Cai, Aubryanna Hettinghouse, Asya Khleborodova, Zi-Ning Lei, Zhe-Sheng Chen, Guang-hua Lei, Chuan-ju Liu
1 December 2021
Exercise and education versus saline injections for knee osteoarthritis: a randomised controlled equivalence trialElisabeth Bandak, Robin Christensen, Anders Overgaard, Lars Erik Kristensen, Karen Ellegaard, Jørgen Guldberg-Møller, Cecilie Bartholdy, David J Hunter, Roy Altman, Henning Bliddal, Marius Henriksen
29 November 2021
14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritisWenyu Fu, Aubryanna Hettinghouse, Yujianan Chen, Wenhuo Hu, Xiang Ding, Meng Chen, Yuanjing Ding, Jyoti Mundra, Wenhao Song, Ronghan Liu, Young-Su Yi, Mukundan Attur, Jonathan Samuels, Eric Strauss, Philipp Leucht
See the full list of authors5 July 2021
circPDE4B prevents articular cartilage degeneration and promotes repair by acting as a scaffold for RIC8A and MID1Shuying Shen, Yute Yang, Panyang Shen, Jun Ma, Bin Fang, Qingxin Wang, Kefan Wang, Peihua Shi, Shunwu Fan, Xiangqian Fang
26 May 2021
Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritisJulia Steinberg, Lorraine Southam, Andreas Fontalis, Matthew J Clark, Raveen L Jayasuriya, Diane Swift, Karan M Shah, Roger A Brooks, Andrew W McCaskie, Jeremy Mark Wilkinson, Eleftheria Zeggini
26 April 2021