Early arthritis

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Is a 1-year course of methotrexate in patients with arthralgia at-risk for rheumatoid arthritis cost-effective? A cost-effectiveness analysis of the randomised, placebo-controlled TREAT EARLIER trial

Elise van Mulligen, Sterre S Bour, Lucas M A Goossens, Pascal Hendrik Pieter de Jong, Maureen Rutten-van Mölken, Annette van der Helm-van Mil

18 September 2024

Association of rheumatoid factor, anti-citrullinated protein antibodies and shared epitope with clinical response to initial treatment in patients with early rheumatoid arthritis: data from a randomised controlled trial

Kristina Lend, Jon Lampa, Leonid Padyukov, Merete Lund Hetland, Marte Schrumpf Heiberg, Dan C Nordström, Michael T Nurmohamed, Anna Rudin, Mikkel Østergaard, Espen A Haavardsholm, Kim Hørslev-Petersen, Till Uhlig, Tuulikki Sokka-Isler, Bjorn Gudbjornsson, Gerdur GrondalSee the full list of authors

30 July 2024

Rheuma-VOR study: optimising healthcare of rheumatic diseases by multiprofessional coordinating centres

Matthias Dreher, Torsten Witte, Kirsten Hoeper, Gunter Assmann, Fabian Proft, Denis Poddubnyy, Niels Murawski, Konstantinos Triantafyllias, Marlon Grodd, Erika Graf, Urs A Fichtner, Harald Binder, Jan Zeidler, Juliana Rachel Hoeper, Johanna CallhoffSee the full list of authors

27 October 2023

Directed differentiation of human pluripotent stem cells into articular cartilage reveals effects caused by absence of WISP3, the gene responsible for progressive pseudorheumatoid arthropathy of childhood

Chaochang Li, Mireia Alemany-Ribes, Rosanne M Raftery, Uzochi Nwoko, Matthew L Warman, April M Craft

7 September 2023

Disease activity drives transcriptomic heterogeneity in early untreated rheumatoid synovitis

Clément Triaille, Gaëlle Tilman, Tatiana Sokolova, Axelle Loriot, Joelle Marchandise, Stéphanie De Montjoye, Adrien Nzeusseu-Toukap, Laurent Méric de Bellefon, Caroline Bouzin, Christine Galant, Patrick Durez, Bernard R Lauwerys, Nisha Limaye

28 July 2023

Tenosynovitis has a high sensitivity for early ACPA-positive and ACPA-negative RA: a large cross-sectional MRI study

Xanthe Marijn Edmée Matthijssen, Fenne Wouters, Navkiran Sidhu, Ellis Niemantsverdriet, Annette van der Helm-van Mil

5 February 2021

Pragmatic randomised controlled trial of very early etanercept and MTX versus MTX with delayed etanercept in RA: the VEDERA trial

Paul Emery, Sarah Horton, Raluca Bianca Dumitru, Kamran Naraghi, Désirée van der Heijde, Richard J Wakefield, Elizabeth M A Hensor, Maya H Buch

29 January 2020

FGFR3 deficiency enhances CXCL12-dependent chemotaxis of macrophages via upregulating CXCR7 and aggravates joint destruction in mice

Liang Kuang, Jiangyi Wu, Nan Su, Huabing Qi, Hangang Chen, Siru Zhou, Yan Xiong, Xiaolan Du, Qiaoyan Tan, Jing Yang, Min Jin, Fengtao Luo, Junjie Ouyang, Bin Zhang, Zuqiang WangSee the full list of authors

29 October 2019

Synovial tissue signatures enhance clinical classification and prognostic/treatment response algorithms in early inflammatory arthritis and predict requirement for subsequent biological therapy: results from the pathobiology of early arthritis cohort (PEAC)

Gloria Lliso-Ribera, Frances Humby, Myles Lewis, Alessandra Nerviani, Daniele Mauro, Felice Rivellese, Stephen Kelly, Rebecca Hands, Fabiola Bene, Nandhini Ramamoorthi, Jason A Hackney, Alberto Cauli, Ernest H Choy, Andrew Filer, Peter C TaylorSee the full list of authors

2 October 2019

Synovial cellular and molecular signatures stratify clinical response to csDMARD therapy and predict radiographic progression in early rheumatoid arthritis patients

Frances Humby, Myles Lewis, Nandhini Ramamoorthi, Jason A Hackney, Michael R Barnes, Michele Bombardieri, A. Francesca Setiadi, Stephen Kelly, Fabiola Bene, Maria DiCicco, Sudeh Riahi, Vidalba Rocher, Nora Ng, Ilias Lazarou, Rebecca HandsSee the full list of authors

16 March 2019