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Extended colonic ulcerations in a patient with microscopic polyangiitis
  1. C-N Tsai1,
  2. C-M Chang2,
  3. C-H Chuang3,
  4. Y-T Jin4,
  5. M-F Liu1,
  6. C-R Wang1
  1. 1Section of Rheumatology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  2. 2Section of Geriatrics, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  3. 3Section of Gastroenterology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan
  4. 4Department of Pathology, College of Medicine, National Cheng-Kung University, Tainan, Taiwan
  1. Correspondence to:
    Dr C-R Wang
    Section of Rheumatology and Section of Allergy and Immunology, Department of Internal Medicine, College of Medicine, National Cheng Kung University, No 1, University Road, Tainan, Taiwan; wangcrmail.ncku.edu.tw

https://doi.org/10.1136/ard.2003.018580

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    Microscopic polyangiitis is a necrotising vasculitis primarily affecting small vessels, with few or no immune deposits. Patients are characterised by positive antineutrophil cytoplasmic antibodies (ANCA), mainly perinuclear pattern. The spectrum of clinical manifestations is broad, including the kidney, musculoskeletal system, lung, gastrointestinal tract, skin, ear, nose, and throat, and neurological system.1 Although gastrointestinal disease is noted in half of the patients, the presentation is usually mild.2 Here, we report a patient with microscopic polyangiitis with initial presentation of extended colonic ulcerations and haemorrhage, characterised by a crypt abscess. To our knowledge, such a finding has not been reported previously.

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