Poly(ADP-ribose) polymerases (PARPs) are DNA-dependent nuclear enzymes that transfer
negatively charged ADP-ribose moieties from cellular nicotinamide-adenine-dinucleotide (…

To coordinate, adapt and respond to biological signals, cells convey specific messages to
other cells. An important aspect of cell–cell communication involves secretion of molecules …

Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound carriers
with complex cargoes including proteins, lipids, and nucleic acids. While the release of EVs …

The future climate change results assessed in this chapter are based on a hierarchy of
models, ranging from Atmosphere-Ocean General Circulation Models (AOGCMs) and Earth …

Climate–Carbon Cycle Feedback Analysis: Results from the C4MIP Model Intercomparison in:
Journal of Climate Volume 19 Issue 14 (2006) Jump to Content Jump to Main Navigation Logo …

This chapter assesses long-term projections of climate change for the end of the 21st century
and beyond, where the forced signal depends on the scenario and is typically larger than …

The Atlantic thermohaline circulation (THC) is an important part of the earth's climate system.
Previous research has shown large uncertainties in simulating future changes in this critical …

Purpose : We examined the relationship between tumor size and malignancy among solid
renal tumors, and the relationship between tumor size and RCC subtype within tumors with …

Purpose : Currently outcome prediction in renal cell carcinoma is largely based on pathological
stage and tumor grade. We developed an outcome prediction model for patients treated …

This chapter assesses the processes in the climate system that are believed to contribute
the most to the uncertainties in current projections of greenhouse warming. Many of these …