User profiles for "author:Ziyun Wan"

Ziyun Wan

BGI-research
Verified email at genomics.cn
Cited by 255

[PDF][PDF] Distinct biological ages of organs and systems identified from a multi-omics study

C Nie, Y Li, R Li, Y Yan, D Zhang, T Li, Z Li, Y Sun… - Cell reports, 2022 - cell.com
Biological age (BA) has been proposed to evaluate the aging status instead of chronological
age (CA). Our study shows evidence that there might be multiple" clocks" within the whole …

T cell receptor β repertoires as novel diagnostic markers for systemic lupus erythematosus and rheumatoid arthritis

X Liu, W Zhang, M Zhao, L Fu, L Liu, J Wu… - Annals of the …, 2019 - ard.bmj.com
Objective T cell receptor (TCR) diversity determines the autoimmune responses in systemic
lupus erythematosus (SLE) and rheumatoid arthritis (RA) and is closely associated with …

[HTML][HTML] Genome-Wide Identification of Petunia HSF Genes and Potential Function of PhHSF19 in Benzenoid/Phenylpropanoid Biosynthesis

J Fu, S Huang, J Qian, H Qing, Z Wan, H Cheng… - International journal of …, 2022 - mdpi.com
Volatile benzenoids/phenylpropanoids are the main flower scent compounds in petunia
(Petunia hybrida). Heat shock factors (HSFs), well known as the main regulator of heat …

[PDF][PDF] Single-cell transcriptomic landscape of nucleated cells in umbilical cord blood

Y Zhao, X Li, W Zhao, J Wang, J Yu, Z Wan, K Gao… - …, 2019 - academic.oup.com
Background For both pediatric and adult patients, umbilical cord blood (UCB) transplant is a
therapeutic option for a variety of hematologic diseases, such as blood cancers …

[HTML][HTML] Germline-encoded TCR-MHC contacts promote TCR V gene bias in umbilical cord blood T cell repertoire

K Gao, L Chen, Y Zhang, Y Zhao, Z Wan, J Wu… - Frontiers in …, 2019 - frontiersin.org
T cells recognize antigens as peptides bound to major histocompatibility complex (MHC)
proteins through T cell receptors (TCRs) on their surface. To recognize a wide range of …

[PDF][PDF] A population-based study of precision health assessments using multi-omics network-derived biological functional modules

W Zhang, Z Wan, X Li, R Li, L Luo, Z Song, Y Miao… - Cell Reports …, 2022 - cell.com
Recent technological advances in multi-omics and bioinformatics provide an opportunity to
develop precision health assessments, which require big data and relevant bioinformatic …

[HTML][HTML] ZeMYB9 regulates cyanidin synthesis by activating the expression of flavonoid 3′-hydroxylase gene in Zinnia elegans

J Qian, L Jiang, H Qing, J Chen, Z Wan, M Xu… - Frontiers in Plant …, 2022 - frontiersin.org
Petal color in Zinnia elegans is characterized mainly by anthocyanin accumulation. The
difference in the content of anthocyanins, especially cyanidins, affects petal coloration in Z …

[HTML][HTML] Single-cell RNA-seq unveils critical regulators of human FOXP3+ regulatory T cell stability

G Yi, Y Zhao, F Xie, F Zhu, Z Wan, J Wang, X Wang… - Science Bulletin, 2020 - Elsevier
The heterogeneity and plasticity of T lymphocytes is critical for determining immune
response outcomes. Functional regulatory T (Treg) cells are commonly characterized by …

Transcriptome and photosynthetic analyses provide new insight into the molecular mechanisms underlying heat stress tolerance in Rhododendron × pulchrum Sweet

H Cheng, Z Wan, Y Xu, J Shen, X Li, S Jin - Tree Physiology, 2024 - academic.oup.com
Rhododendron species provide excellent ornamental use worldwide, yet heat stress (HS) is
one of the major threats to their cultivation. However, the intricate mechanisms underlying …

[HTML][HTML] Comprehensive Genomic Survey, Structural Classification, and Expression Analysis of WRKY Transcription Factor  Family in Rhododendron simsii

Z Wan, X Li, H Cheng, J Zhang, Y Chen, Y Xu, S Jin - Plants, 2022 - mdpi.com
(1) Rhododendron is one of the top ten traditional flowers in China, with both high
ornamental and economic values. However, with the change of the environment …