Oxidative stress and metal carcinogenesis
JC Lee, YO Son, P Pratheeshkumar, X Shi - Free radical biology and …, 2012 - Elsevier
Occupational and environmental exposures to metals are closely associated with an
increased risk of various cancers. Although carcinogenesis caused by metals has been …
increased risk of various cancers. Although carcinogenesis caused by metals has been …
Cancer prevention with promising natural products: mechanisms of action and molecular targets
P Pratheeshkumar, C Sreekala, Z Zhang… - Anti-Cancer Agents …, 2012 - ingentaconnect.com
Cancer is the second leading cause of death worldwide. There is greater need for more
effective and less toxic therapeutic and preventive strategies. Natural products are becoming …
effective and less toxic therapeutic and preventive strategies. Natural products are becoming …
[HTML][HTML] Metal-based nanoparticles and their relevant consequences on cytotoxicity cascade and induced oxidative stress
Emerging nanoscience allows us to take advantage of the improved evolutionary
components and apply today's advanced characterization and fabrication techniques to …
components and apply today's advanced characterization and fabrication techniques to …
[HTML][HTML] Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR-2 regulated AKT/mTOR/P70S6K signaling pathways
P Pratheeshkumar, A Budhraja, YO Son, X Wang… - 2012 - journals.plos.org
Angiogenesis is a crucial step in the growth and metastasis of cancers, since it enables the
growing tumor to receive oxygen and nutrients. Cancer prevention using natural products …
growing tumor to receive oxygen and nutrients. Cancer prevention using natural products …
The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis
WS Choi, G Lee, WH Song, JT Koh, J Yang, JS Kwak… - Nature, 2019 - nature.com
Osteoarthritis—the most common form of age-related degenerative whole-joint disease—is
primarily characterized by cartilage destruction, as well as by synovial inflammation …
primarily characterized by cartilage destruction, as well as by synovial inflammation …
Increase of NKG2D ligands and sensitivity to NK cell-mediated cytotoxicity of tumor cells by heat shock and ionizing radiation
JY Kim, YO Son, SW Park, JH Bae, JS Chung… - … & molecular medicine, 2006 - nature.com
In this study, we have investigated if current cancer therapeutic modalities including
hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in …
hyperthermia and ionizing radiation can increase the expression of NKG2D ligands in …
Quercitrin protects skin from UVB-induced oxidative damage
Exposure of the skin to ultraviolet B (UVB) radiation causes oxidative damage to skin,
resulting in sunburn, photoaging, and skin cancer. It is generally believed that the skin …
resulting in sunburn, photoaging, and skin cancer. It is generally believed that the skin …
Cadmium induces autophagy through ROS-dependent activation of the LKB1–AMPK signaling in skin epidermal cells
Cadmium is a toxic heavy metal which is environmentally and occupationally relevant. The
mechanisms underlying cadmium-induced autophagy are not yet completely understood …
mechanisms underlying cadmium-induced autophagy are not yet completely understood …
[HTML][HTML] Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis
P Pratheeshkumar, YO Son, A Budhraja, X Wang… - PloS one, 2012 - journals.plos.org
Angiogenesis, the formation of new blood vessels from pre-existing vascular beds, is
essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid …
essential for tumor growth, invasion, and metastasis. Luteolin is a common dietary flavonoid …
Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling
Cadmium has been widely used in industry and is known to be carcinogenic to humans.
Although it is widely accepted that chronic exposure to cadmium increases the incidence of …
Although it is widely accepted that chronic exposure to cadmium increases the incidence of …