[HTML][HTML] Disease-modifying therapeutic strategies in osteoarthritis: current status and future directions
Osteoarthritis (OA) is the most common form of arthritis. It is characterized by progressive
destruction of articular cartilage and the development of chronic pain and constitutes a …
destruction of articular cartilage and the development of chronic pain and constitutes a …
[HTML][HTML] Epigenetic regulation of chondrocyte catabolism and anabolism in osteoarthritis
H Kim, D Kang, Y Cho, JH Kim - Molecules and cells, 2015 - Elsevier
Osteoarthritis (OA) is one of the most prevalent forms of joint disorder, associated with a
tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related …
tremendous socioeconomic burden worldwide. Various non-genetic and lifestyle-related …
Stress-activated miR-204 governs senescent phenotypes of chondrocytes to promote osteoarthritis development
A progressive loss of cartilage matrix leads to the development of osteoarthritis (OA). Matrix
homeostasis is disturbed in OA cartilage as the result of reduced production of cartilage …
homeostasis is disturbed in OA cartilage as the result of reduced production of cartilage …
A fully integrated CMOS frequency synthesizer with charge-averaging charge pump and dual-path loop filter for PCS-and cellular-CDMA wireless systems
Y Koo, H Huh, Y Cho, J Lee, J Park… - IEEE Journal of solid …, 2002 - ieeexplore.ieee.org
A fully integrated CMOS frequency synthesizer for PCS-and cellular-CDMA systems is
integrated in a 0.35-/spl mu/m CMOS technology. The proposed charge-averaging charge …
integrated in a 0.35-/spl mu/m CMOS technology. The proposed charge-averaging charge …
CTRP3 exacerbates tendinopathy by dysregulating tendon stem cell differentiation and altering extracellular matrix composition
Y Cho, HS Kim, D Kang, H Kim, N Lee, J Yun… - Science …, 2021 - science.org
Tendinopathy, the most common disorder affecting tendons, is characterized by chronic
disorganization of the tendon matrix, which leads to tendon tear and rupture. The goal was …
disorganization of the tendon matrix, which leads to tendon tear and rupture. The goal was …
Pleiotropic roles of metallothioneins as regulators of chondrocyte apoptosis and catabolic and anabolic pathways during osteoarthritis pathogenesis
Y Won, Y Shin, CH Chun, Y Cho, CW Ha… - Annals of the …, 2016 - ard.bmj.com
Objective The zinc-ZIP8-MTF1 axis induces metallothionein (MT) expression and is a
catabolic regulator of experimental osteoarthritis (OA) in mice. The main aim of the current …
catabolic regulator of experimental osteoarthritis (OA) in mice. The main aim of the current …
[HTML][HTML] Tankyrase inhibition preserves osteoarthritic cartilage by coordinating cartilage matrix anabolism via effects on SOX9 PARylation
S Kim, S Han, Y Kim, HS Kim, YR Gu, D Kang… - Nature …, 2019 - nature.com
Osteoarthritis (OA) is a prevalent degenerative disease, which involves progressive and
irreversible destruction of cartilage matrix. Despite efforts to reconstruct cartilage matrix in …
irreversible destruction of cartilage matrix. Despite efforts to reconstruct cartilage matrix in …
[HTML][HTML] A system-level approach identifies HIF-2α as a critical regulator of chondrosarcoma progression
H Kim, Y Cho, HS Kim, D Kang, D Cheon… - Nature …, 2020 - nature.com
Chondrosarcomas, malignant cartilaginous neoplasms, are capable of transitioning to highly
aggressive, metastatic, and treatment-refractory states, resulting in significant patient …
aggressive, metastatic, and treatment-refractory states, resulting in significant patient …
IRF1 deficiency predisposes cartilage to accumulate DNA damage and promotes osteoarthritis development
Y Cho, H Kim, G Yook, S Yong, S Kim… - Arthritis & …, 2024 - Wiley Online Library
Objective Interferon regulatory factor 1 (IRF1) is a transcriptional regulator conventionally
associated with immunomodulation. Recent molecular analyses mapping DNA binding sites …
associated with immunomodulation. Recent molecular analyses mapping DNA binding sites …
Effect of ascorbic acid and protein concentration on the molecular weight profile of bovine serum albumin and β-lactoglobulin by γ-irradiation
Y Cho, JS Yang, KB Song - Food research international, 1999 - Elsevier
The effects of ascorbic acid and protein concentration on the molecular weight size
distribution of BSA and β-lactoglobulin were examined after irradiation of proteins at various …
distribution of BSA and β-lactoglobulin were examined after irradiation of proteins at various …