[HTML][HTML] Engineered mesenchymal stem cell-derived extracellular vesicles: a state-of-the-art multifunctional weapon against Alzheimer's disease

T Yin, Y Liu, W Ji, J Zhuang, X Chen, B Gong, J Chu… - Theranostics, 2023 - ncbi.nlm.nih.gov
With the increase of population aging, the number of Alzheimer's disease (AD) patients is
also increasing. According to current estimates, approximately 11% of people over 65 suffer …

[HTML][HTML] DNA methylation-free Arabidopsis reveals crucial roles of DNA methylation in regulating gene expression and development

L He, H Huang, M Bradai, C Zhao, Y You, J Ma… - Nature …, 2022 - nature.com
A contribution of DNA methylation to defense against invading nucleic acids and
maintenance of genome integrity is uncontested; however, our understanding of the extent …

Risk of serious infection with biologic and systemic treatment of psoriasis: results from the Psoriasis Longitudinal Assessment and Registry (PSOLAR)

RE Kalb, DF Fiorentino, MG Lebwohl, J Toole… - JAMA …, 2015 - jamanetwork.com
Importance The efficacy of treatment for psoriasis must be balanced against potential
adverse events. Objective To determine the effect of treatment on the risk of serious …

[HTML][HTML] Telbivudine versus lamivudine in Chinese patients with chronic hepatitis B: Results at 1 year of a randomized, double‐blind trial

J Hou, YK Yin, D Xu, D Tan, J Niu, X Zhou… - …, 2008 - Wiley Online Library
Chronic hepatitis B and its life‐threatening sequelae are highly prevalent in China. There is
a need for effective new therapies to suppress hepatitis B virus (HBV) replication and …

Coexistence of hepatitis B surface antigen (HBsAg) and heterologous subtype-specific antibodies to HBsAg among patients with chronic hepatitis B virus infection

JM Zhang, Y Xu, XY Wang, YK Yin… - Clinical infectious …, 2007 - academic.oup.com
Background. The coexistence of hepatitis B surface antigen (HBsAg) and antibodies to
HBsAg (anti-HBs) in patients with chronic hepatitis B virus (HBV) infection has been …

Efficacy and safety of ustekinumab in psoriatic arthritis patients with peripheral arthritis and physician-reported spondylitis: post-hoc analyses from two phase III …

A Kavanaugh, L Puig, AB Gottlieb, C Ritchlin… - Annals of the …, 2016 - ard.bmj.com
Objective To evaluate ustekinumab efficacy and safety in psoriatic arthritis (PsA) patients
with peripheral arthritis and physician-reported spondylitis (termed the 'spondylitis subset') …

Nanoparticles-based anti-aging treatment of Alzheimer's disease

JJ Chu, WB Ji, JH Zhuang, BF Gong, XH Chen… - Drug …, 2022 - Taylor & Francis
Age is the strongest risk factor for Alzheimer's disease (AD). In recent years, the relationship
between aging and AD has been widely studied, with anti-aging therapeutics as the …

[HTML][HTML] A 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate …

S Xiao, P Chan, T Wang, Z Hong, S Wang… - Alzheimer's Research & …, 2021 - Springer
Background New therapies are urgently needed for Alzheimer's disease (AD). Sodium
oligomannate (GV-971) is a marine-derived oligosaccharide with a novel proposed …

Underdiagnosis and undertreatment of cardiovascular risk factors in patients with moderate to severe psoriasis

AB Kimball, P Szapary, U Mrowietz, K Reich… - Journal of the American …, 2012 - Elsevier
BACKGROUND: Patients with psoriasis are known to have an increased number of
cardiovascular (CV) risk factors and be at increased risk for CV events. OBJECTIVES: We …

[HTML][HTML] Recommendations for the diagnosis and treatment of paroxysmal kinesigenic dyskinesia: an expert consensus in China

L Cao, X Huang, N Wang, Z Wu, C Zhang, W Gu… - Translational …, 2021 - Springer
Paroxysmal dyskinesias are a group of neurological diseases characterized by intermittent
episodes of involuntary movements with different causes. Paroxysmal kinesigenic …