[HTML][HTML] Oct4 transcriptionally regulates the expression of long non-coding RNAs NEAT1 and MALAT1 to promote lung cancer progression

J Jen, YA Tang, YH Lu, CC Lin, WW Lai, YC Wang - Molecular cancer, 2017 - Springer
Background Oct4, a key stemness transcription factor, is overexpressed in lung cancer.
Here, we reveal a novel transcription regulation of long non-coding RNAs (lncRNAs) by …

Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression

IY Kuo, CC Wu, JM Chang, YL Huang… - … journal of cancer, 2014 - Wiley Online Library
The transcriptional network of the SRY (sex determining region Y)‐box 17 (SOX17) and the
prognostic impact of SOX17 protein expression in human cancers remain largely unclear. In …

Metformin enhances cisplatin cytotoxicity by suppressing signal transducer and activator of transcription–3 activity independently of the liver kinase B1–AMP-activated …

CC Lin, HH Yeh, WL Huang, JJ Yan… - American journal of …, 2013 - atsjournals.org
Metformin has been used as first-line treatment in patients with type 2 diabetes, and is
reported to reduce cancer risk and progression by activating the liver kinase B1 (LKB1) …

Thymic carcinoma: involvement of great vessels indicates poor prognosis

YL Tseng, ST Wang, MH Wu, MY Lin, WW Lai… - The Annals of thoracic …, 2003 - Elsevier
BACKGROUND: Thymic carcinoma is a rare, indolent, and invasive cancer. This study
investigated the treatment results of thymic carcinoma and clinical prognostic factors …

[HTML][HTML] Psychometric evaluation of the WHOQOL-BREF, Taiwan version, across five kinds of Taiwanese cancer survivors: Rasch analysis and confirmatory factor …

CY Lin, JS Hwang, WC Wang, WW Lai, WC Su… - Journal of the Formosan …, 2019 - Elsevier
Background Quality of life (QoL) is important for clinicians to evaluate how cancer survivors
judge their sense of well-being, and WHOQOL-BREF may be a good tool for clinical use …

Epstein‐barr virus‐associated nonsmall cell lung carcinoma: Undifferentiated" lymphoepithelioma‐like" carcinoma as a distinct entity with better prognosis

FF Chen, JJ Yan, WW Lai, YT Jin… - … International Journal of …, 1998 - Wiley Online Library
Abstract BACKGROUND Epstein‐Barr virus (EBV) infection in nonsmall cell lung carcinoma
(NSCLC) has been demonstrated in some ethnic groups. The pathobiology and the role of …

[HTML][HTML] Signal transducer and activator of transcription 3 activation up-regulates interleukin-6 autocrine production: a biochemical and genetic study of established …

WL Huang, HH Yeh, CC Lin, WW Lai, JY Chang… - Molecular cancer, 2010 - Springer
Abstract Background Spontaneous interleukin-6 (IL-6) production has been observed in
various tumors and implicated in the pathogenesis, progression and drug resistance in …

[HTML][HTML] Ubiquitination of tumor suppressor PML regulates prometastatic and immunosuppressive tumor microenvironment

YT Wang, J Chen, CW Chang, J Jen… - The Journal of …, 2017 - Am Soc Clin Investig
The tumor microenvironment plays an important role in tumor growth and metastasis.
However, the mechanism by which tumor cells regulate the cell and non-cell constituents of …

Apolipoprotein E expression promotes lung adenocarcinoma proliferation and migration and as a potential survival marker in lung cancer

WP Su, YT Chen, WW Lai, CC Lin, JJ Yan, WC Su - Lung Cancer, 2011 - Elsevier
Many human lung cancer cell lines express apolipoprotein E (ApoE), especially cells
derived from malignant pleural effusions (MPE) in patients with lung adenocarcinoma. This …

Predictive and prognostic value of human copper transporter 1 (hCtr1) in patients with stage III non-small-cell lung cancer receiving first-line platinum-based doublet …

HHW Chen, JJ Yan, WC Chen, MT Kuo, YH Lai… - Lung cancer, 2012 - Elsevier
BACKGROUND: Recent studies have shown that human copper transporter 1 (hCtr1), the
major copper influx transporter, is involved in the transport of platinum-based antitumor …