User profiles for "author:W OLLIER"
William OllierProfessor of Immunogenetics, University of Manchester Verified email at manchester.ac.uk Cited by 47104 |
A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip
E Evangelou, HJ Kerkhof, U Styrkarsdottir… - Annals of the …, 2014 - ard.bmj.com
Objectives Osteoarthritis (OA) is the most common form of arthritis with a clear genetic
component. To identify novel loci associated with hip OA we performed a meta-analysis of …
component. To identify novel loci associated with hip OA we performed a meta-analysis of …
Genetic markers of disease susceptibility and severity in giant cell arteritis and polymyalgia rheumatica
MA González-Gay, MM Amoli, C Garcia-Porrua… - Seminars in arthritis and …, 2003 - Elsevier
Background and Objectives: Giant cell arteritis (GCA) and polymyalgia rheumatica (PMR)
are common and often overlapping diseases that generally occur in elderly patients. In this …
are common and often overlapping diseases that generally occur in elderly patients. In this …
Population genetics of rheumatoid arthritis
It is now a considerable number of years since the first report of an association between
rheumatoid arthritis (RA) and Dw4/DR4. 98, 99 In this timet the human leukocyte antigen …
rheumatoid arthritis (RA) and Dw4/DR4. 98, 99 In this timet the human leukocyte antigen …
Genome-wide association study identifies 74 loci associated with educational attainment
Educational attainment is strongly influenced by social and other environmental factors, but
genetic factors are estimated to account for at least 20% of the variation across individuals 1 …
genetic factors are estimated to account for at least 20% of the variation across individuals 1 …
Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence
Intelligence is highly heritable and a major determinant of human health and well-being.
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in …
Twin concordance rates for rheumatoid arthritis: results from a nationwide study
We report the concordance rate for RA in a nationwide study of 91 monozygotic (MZ) and
112 dizygotic (DZ) pairs. Twin pairs were recruited from both a national media campaign …
112 dizygotic (DZ) pairs. Twin pairs were recruited from both a national media campaign …
[PDF][PDF] Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations
CG Boer, K Hatzikotoulas, L Southam, L Stefánsdóttir… - Cell, 2021 - cell.com
Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …
[HTML][HTML] Study of 300,486 individuals identifies 148 independent genetic loci influencing general cognitive function
General cognitive function is a prominent and relatively stable human trait that is associated
with many important life outcomes. We combine cognitive and genetic data from the …
with many important life outcomes. We combine cognitive and genetic data from the …
Genome-wide association study identifies variants in the MHC class I, IL10, and IL23R-IL12RB2 regions associated with Behçet's disease
Behçet's disease is a genetically complex disease of unknown etiology characterized by
recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed …
recurrent inflammatory attacks affecting the orogenital mucosa, eyes and skin. We performed …
Genome-wide association studies establish that human intelligence is highly heritable and polygenic
General intelligence is an important human quantitative trait that accounts for much of the
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …
variation in diverse cognitive abilities. Individual differences in intelligence are strongly …