Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis

P Tynjälä, P Lindahl, V Honkanen… - Annals of the …, 2007 - ard.bmj.com
Objective: To evaluate the efficacy of anti-tumour necrosis factor (anti-TNF) treatment in
juvenile idiopathic arthritis (JIA)-associated uveitis. Methods: 24 patients with uveitis taking …

Adalimumab in juvenile idiopathic arthritis-associated chronic anterior uveitis

P Tynjälä, K Kotaniemi, P Lindahl, K Latva… - …, 2008 - academic.oup.com
Objective. To evaluate the efficacy of adalimumab in juvenile idiopathic arthritis (JIA)-
associated uveitis. Methods. Retrospective observational study of 20 patients with JIA and …

Aggressive combination drug therapy in very early polyarticular juvenile idiopathic arthritis (ACUTE–JIA): a multicentre randomised open-label clinical trial

P Tynjälä, P Vähäsalo, M Tarkiainen… - Annals of the …, 2011 - ard.bmj.com
Objectives In juvenile idiopathic arthritis (JIA), the efficacy of very early disease-modifying
drug therapy, synthetic or biological, is not well known. Three alternative strategies were …

Impact of anti-TNF treatment on growth in severe juvenile idiopathic arthritis

P Tynjälä, P Lahdenne, P Vähäsalo… - Annals of the …, 2006 - ard.bmj.com
Objectives: To evaluate the impact of anti-tumour necrosis factor (TNF) treatment on growth
and to identify the predictors for the change in growth in severe juvenile idiopathic arthritis …

Drug survival of the first and second course of anti-tumour necrosis factor agents in juvenile idiopathic arthritis

P Tynjälä, P Vähäsalo, V Honkanen… - Annals of the rheumatic …, 2009 - ard.bmj.com
Objectives: To evaluate drug survival (continuation rates on drug) of anti-tumour necrosis
factor (TNF) agents in juvenile idiopathic arthritis (JIA) and predictors for treatment …

Prevalence of vertebral compression fractures and associated factors in children and adolescents with severe juvenile idiopathic arthritis

KP Markula-Patjas, HL Valta, LI Kerttula… - The Journal of …, 2012 - jrheum.org
Objective. Vertebral fractures occur in patients with juvenile idiopathic arthritis (JIA), but data
on their frequency and causes are scarce. Our cross-sectional study evaluated prevalence …

Teaching of patients undergoing total hip replacement surgery

N Santavirta, G Lillqvist, A Sarvimäki… - International journal of …, 1994 - Elsevier
We studied the effect of patient teaching in 60 patients who underwent primary total hip
replacement surgery. All the patients received an illustrated patient guide. In addition to the …

Effects of infliximab on cytokines, myeloperoxidase, and soluble adhesion molecules in patients with juvenile idiopathic arthritis

T Levälampi, V Honkanen, P Lahdenne… - Scandinavian journal …, 2007 - Taylor & Francis
Objective: Infliximab is effective and well tolerated in the treatment of juvenile idiopathic
arthritis (JIA). The aim of the present study was to measure circulating levels of inflammatory …

Ten-year results of operations for rheumatoid cervical spine disorders

S Santavirta, YT Konttinen, E Laasonen… - The Journal of Bone …, 1991 - boneandjoint.org.uk
The outcome of operations performed on 38 patients for rheumatoid disorders of the cervical
spine were analysed 10 or more years later. The mean age of the patients at the time of …

A three‐stage clinical trial design for rare disorders

VEA Honkanen, AF Siegel, JP Szalai… - Statistics in …, 2001 - Wiley Online Library
Many clinical trials of uncommon diseases are underpowered because of the difficulty of
recruiting adequate numbers of subjects. We propose a clinical trial design with improved …