User profiles for "author:Ung-il Chung"
Ung-il ChungUniversity of Tokyo Schools of Engineering and Medicine; Kanagawa University of Human … Verified email at tetrapod.tu-tokyo.ac.jp Cited by 23431 |
Design of hydrogels for biomedical applications
Hydrogels are considered key tools for the design of biomaterials, such as wound dressings,
drug reservoirs, and temporary scaffolds for cells. Despite their potential, conventional …
drug reservoirs, and temporary scaffolds for cells. Despite their potential, conventional …
[HTML][HTML] Understanding paraxial mesoderm development and sclerotome specification for skeletal repair
Pluripotent stem cells (PSCs) are attractive regenerative therapy tools for skeletal tissues.
However, a deep understanding of skeletal development is required in order to model this …
However, a deep understanding of skeletal development is required in order to model this …
Design and fabrication of a high-strength hydrogel with ideally homogeneous network structure from tetrahedron-like macromonomers
T Sakai, T Matsunaga, Y Yamamoto, C Ito… - …, 2008 - ACS Publications
As a new class of high-strength hydrogels, we designed a tetra-PEG gel by combining two
symmetrical tetrahedron-like macromonomers of the same size. Because the nanostructural …
symmetrical tetrahedron-like macromonomers of the same size. Because the nanostructural …
[HTML][HTML] PPAR γ insufficiency enhances osteogenesis through osteoblast formation from bone marrow progenitors
T Akune, S Ohba, S Kamekura… - The Journal of …, 2004 - Am Soc Clin Investig
Based on the fact that aging is associated with a reciprocal decrease of osteogenesis and
an increase of adipogenesis in bone marrow and that osteoblasts and adipocytes share a …
an increase of adipogenesis in bone marrow and that osteoblasts and adipocytes share a …
Surface grafting of artificial joints with a biocompatible polymer for preventing periprosthetic osteolysis
T Moro, Y Takatori, K Ishihara, T Konno, Y Takigawa… - Nature materials, 2004 - nature.com
Periprosthetic osteolysis—bone loss in the vicinity of a prosthesis—is the most serious
problem limiting the longevity of artificial joints. It is caused by bone-resorptive responses to …
problem limiting the longevity of artificial joints. It is caused by bone-resorptive responses to …
“Nonswellable” hydrogel without mechanical hysteresis
Hydrogels are three-dimensional polymer networks that contain a large amount of water
inside. Certain hydrogels can be injected in solution and transformed into the gel state with …
inside. Certain hydrogels can be injected in solution and transformed into the gel state with …
Transcriptional regulation of endochondral ossification by HIF-2α during skeletal growth and osteoarthritis development
Chondrocyte hypertrophy followed by cartilage matrix degradation and vascular invasion,
characterized by expression of type X collagen (COL10A1), matrix metalloproteinase-13 …
characterized by expression of type X collagen (COL10A1), matrix metalloproteinase-13 …
Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton
Indian hedgehog (Ihh) is indispensable for development of the osteoblast lineage in the
endochondral skeleton. In order to determine whether Ihh is directly required for osteoblast …
endochondral skeleton. In order to determine whether Ihh is directly required for osteoblast …
[HTML][HTML] Indian hedgehog couples chondrogenesis to osteogenesis in endochondral bone development
Vertebrate skeletogenesis requires a well-coordinated transition from chondrogenesis to
osteogenesis. Hypertrophic chondrocytes in the growth plate play a pivotal role in this …
osteogenesis. Hypertrophic chondrocytes in the growth plate play a pivotal role in this …
The combination of SOX5, SOX6, and SOX9 (the SOX trio) provides signals sufficient for induction of permanent cartilage
T Ikeda, S Kamekura, A Mabuchi, I Kou… - Arthritis & …, 2004 - Wiley Online Library
Objective To regenerate permanent cartilage, it is crucial to know not only the necessary
conditions for chondrogenesis, but also the sufficient conditions. The objective of this study …
conditions for chondrogenesis, but also the sufficient conditions. The objective of this study …