Humoral and T-cell responses to SARS-CoV-2 vaccination in patients receiving immunosuppression

M Prendecki, C Clarke, H Edwards… - Annals of the …, 2021 - ard.bmj.com
Objective There is an urgent need to assess the impact of immunosuppressive therapies on
the immunogenicity and efficacy of SARS-CoV-2 vaccination. Methods Serological and T …

Immunological responses to SARS-CoV-2 vaccines in kidney transplant recipients

M Prendecki, T Thomson, CL Clarke, P Martin… - The Lancet, 2021 - thelancet.com
Data are shown as median with IQR. Statistical analysis is by MannWhitney test (A) or
KruskallWallis test with Dunns posthoc correction (B).(A) Kidney transplant recipients who …

[HTML][HTML] Immune responses following 3rd and 4th doses of heterologous and homologous COVID-19 vaccines in kidney transplant recipients

T Thomson, M Prendecki, S Gleeson, P Martin… - …, 2022 - thelancet.com
Background Solid organ transplant recipients have attenuated immune responses to SARS-
CoV-2 vaccines. In this study, we report on immune responses to 3rd-(V3) and 4th-(V4) …

[HTML][HTML] Comparison of vaccine effectiveness against the omicron (B. 1.1. 529) variant in hemodialysis patients

KJ Spensley, S Gleeson, P Martin, T Thomson… - Kidney international …, 2022 - Elsevier
Results A total of 1121 in-center hemodialysis patients were included in the analysis; all
patients underwent weekly screening for SARS-CoV-2 infection via reverse transcriptase …

[HTML][HTML] Comparison of immunogenicity and clinical effectiveness between BNT162b2 and ChAdOx1 SARS-CoV-2 vaccines in people with end-stage kidney disease …

P Martin, S Gleeson, CL Clarke, T Thomson… - The Lancet Regional …, 2022 - thelancet.com
Background People with end-stage kidney disease, including people on haemodialysis, are
susceptible to greater COVID-19 related morbidity and mortality. This study compares the …

[HTML][HTML] Cohort study of outpatient hemodialysis management strategies for COVID-19 in North-West London

NR Medjeral-Thomas, T Thomson, D Ashby… - Kidney international …, 2020 - Elsevier
Background Dialysis patients are at risk of severe coronavirus disease 2019 (COVID-19).
We managed COVID-19 hemodialysis outpatients in dedicated satellite dialysis units. This …

Comparison of humoral and cellular responses in kidney transplant recipients receiving BNT162b2 and ChAdOx1 SARS-CoV-2 vaccines

M Prendecki, T Thomson, CL Clarke, P Martin… - MedRxiv, 2021 - medrxiv.org
Background Attenuated immune responses to mRNA SARS-CoV-2 vaccines have been
reported in solid organ transplant recipients. Most studies have assessed serological …

Comparison of immunogenicity between BNT162b2 and ChAdOx1 SARS-CoV-2 vaccines in a large haemodialysis population

CL Clarke, P Martin, S Gleeson, T Thomson… - Medrxiv, 2021 - medrxiv.org
Background Limited data exists on the immunogenicity of vector-based SARS-CoV-2
vaccines in patients with kidney disease. Given their use in over 180 countries, such data is …

[HTML][HTML] Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antibody lateral flow assay for antibody prevalence studies following vaccination: a …

A Cann, C Clarke, J Brown, T Thomson… - Wellcome open …, 2021 - ncbi.nlm.nih.gov
Background: Lateral flow immunoassays (LFIAs) are able to achieve affordable, large scale
antibody testing and provide rapid results without the support of central laboratories. As part …

Kidney transplant recipients and omicron: outcomes, effect of vaccines and the efficacy and safety of novel treatments

S Gleeson, P Martin, T Thomson, A Thind, M Prendecki… - medRxiv, 2022 - medrxiv.org
We aimed to describe the outcomes of Omicron infection in kidney transplant recipients
(KTR), compare the efficacy of the community therapeutic interventions and report the safety …