Gout is the most common inflammatory arthritis and one in which pathogenesis and risk
factors are best understood. One of the treatment objectives in current guidelines is 'cure' …

Epidemiological and experimental studies have shown that hyperuricaemia and gout are
intricately linked with hypertension, metabolic syndrome, chronic kidney disease and …

Background Although there has been major progress in gout imaging, no gout classification
criteria currently include advanced imaging techniques. Objective To examine the …

Objectives The study of the proinflammatory role of uric acid has focused on the effects of its
crystals of monosodium urate (MSU). However, little is known whether uric acid itself can …

Multinational evidence-based World Association of Sarcoidosi... : Current Opinion in Pulmonary
Medicine Multinational evidence-based World Association of Sarcoidosis and Other …

Objective To determine which clinical, laboratory, and imaging features most accurately
distinguished gout from non‐gout. Methods We performed a cross‐sectional study of …

Background Because of the changing dietary habits of an aging population, hyperuricemia
is frequently found in combination with other metabolic disorders. Longstanding elevation of …

Objective To examine the performance of ultrasound (US) for the diagnosis of gout using the
presence of monosodium urate monohydrate (MSU) crystals as the gold standard. Methods …

Background: In severe refractory sarcoidosis cases not responding to conventional
immunosuppressive treatment, the third-line tumor necrosis factor-alpha (TNF-α) inhibitors …

Objectives Acute gouty arthritis is caused by endogenously formed monosodium urate
(MSU) crystals, which are potent activators of the NLRP3 inflammasome. However, to induce …