Increased blood lactate levels (hyperlactataemia) are common in critically ill patients.
Although frequently used to diagnose inadequate tissue oxygenation, other processes not …

Objective: To decide whether the use of blood lactate monitoring in critical care practice is
appropriate. We performed a systematic health technology assessment as blood lactate …

Gout is the most common inflammatory arthritis and one in which pathogenesis and risk
factors are best understood. One of the treatment objectives in current guidelines is 'cure' …

Objective Existing criteria for the classification of gout have suboptimal sensitivity and/or
specificity, and were developed at a time when advanced imaging was not available. The …

Rationale: It is unknown whether lactate monitoring aimed to decrease levels during initial
treatment in critically ill patients improves outcome. Objectives: To assess the effect of lactate …

Background Extracorporeal cardiopulmonary resuscitation (CPR) restores perfusion and
oxygenation in a patient who does not have spontaneous circulation. The evidence with …

Objective: The physical examination of peripheral perfusion based on touching the skin or
measuring capillary refill time has been related to the prognosis of patients with circulatory …

Although gout is the most common inflammatory arthritis, it is still frequently misdiagnosed.
New data on imaging and clinical diagnosis have become available since the first EULAR …

Epidemiological and experimental studies have shown that hyperuricaemia and gout are
intricately linked with hypertension, metabolic syndrome, chronic kidney disease and …

Introduction A limitation of pre-hospital monitoring is that vital signs often do not change until
a patient is in a critical stage. Blood lactate levels are suggested as a more sensitive …