User profiles for "author:Thomas Illig"

thomas illig

Verified email at mh-hannover.de
Cited by 191917

[HTML][HTML] KORA-gen-resource for population genetics, controls and a broad spectrum of disease phenotypes

HE Wichmann, C Gieger, T Illig… - Das …, 2005 - thieme-connect.com
KORA-gen ist eine Ressource für die genetisch-epidemiologische Forschung, die sich auf
die KORA-Plattform (Kooperative Gesundheitsforschung in der Region Augsburg) stützt …

Childhood cancer predisposition syndromes—a concise review and recommendations by the Cancer Predisposition Working Group of the Society for Pediatric …

T Ripperger, SS Bielack, A Borkhardt… - American journal of …, 2017 - Wiley Online Library
Heritable predisposition is an important cause of cancer in children and adolescents.
Although a large number of cancer predisposition genes and their associated syndromes …

Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism

E Lattka, T Illig, B Koletzko… - Current opinion in …, 2010 - journals.lww.com
Genetic variants of the FADS1 FADS2 gene cluster as related... : Current Opinion in Lipidology
Genetic variants of the FADS1 FADS2 gene cluster as related to essential fatty acid metabolism …

Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease

H Schunkert, IR König, S Kathiresan, MP Reilly… - Nature …, 2011 - nature.com
We performed a meta-analysis of 14 genome-wide association studies of coronary artery
disease (CAD) comprising 22,233 individuals with CAD (cases) and 64,762 controls of …

Hundreds of variants clustered in genomic loci and biological pathways affect human height

H Lango Allen, K Estrada, G Lettre, SI Berndt… - Nature, 2010 - nature.com
Most common human traits and diseases have a polygenic pattern of inheritance: DNA
sequence variants at many genetic loci influence the phenotype. Genome-wide association …

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes

E Zeggini, LJ Scott, R Saxena, BF Voight, JL Marchini… - Nature …, 2008 - nature.com
Genome-wide association (GWA) studies have identified multiple loci at which common
variants modestly but reproducibly influence risk of type 2 diabetes (T2D),,,,,,,,,,. Established …

Defining the role of common variation in the genomic and biological architecture of adult human height

AR Wood, T Esko, J Yang, S Vedantam, TH Pers… - Nature …, 2014 - nature.com
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-
wide significance that together explained one-fifth of the heritability for adult height. By …

Genome-wide association study reveals genetic risk underlying Parkinson's disease

J Simon-Sanchez, C Schulte, JM Bras, M Sharma… - Nature …, 2009 - nature.com
We performed a genome-wide association study (GWAS) in 1,713 individuals of European
ancestry with Parkinson's disease (PD) and 3,978 controls. After replication in 3,361 cases …

Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma

MF Moffatt, M Kabesch, L Liang, AL Dixon, D Strachan… - Nature, 2007 - nature.com
Asthma is caused by a combination of poorly understood genetic and environmental factors,.
We have systematically mapped the effects of single nucleotide polymorphisms (SNPs) on …

Large-scale association analysis identifies new risk loci for coronary artery disease

CARDIoGRAMplusC4D Consortium, P Deloukas… - Nature …, 2013 - nature.com
Coronary artery disease (CAD) is the commonest cause of death. Here, we report an
association analysis in 63,746 CAD cases and 130,681 controls identifying 15 loci reaching …