[HTML][HTML] The pathways of mitophagy for quality control and clearance of mitochondria

G Ashrafi, TL Schwarz - Cell Death & Differentiation, 2013 - nature.com
Selective autophagy of mitochondria, known as mitophagy, is an important mitochondrial
quality control mechanism that eliminates damaged mitochondria. Mitophagy also mediates …

Distinctive pharmacology and kinetics of cloned neuronal Ca2+ channels and their possible counterparts in mammalian CNS neurons

JF Zhang, AD Randall, PT Ellinor, WA Horne… - …, 1993 - Elsevier
This paper provides a brief overview of the diversity of voltage-gated Ca 2+ channels and
our recent work on neuronal Ca 2+ channels with novel pharmacological and biophysical …

Mitochondrial trafficking in neurons

TL Schwarz - Cold Spring Harbor perspectives in biology, 2013 - cshperspectives.cshlp.org
Neurons, perhaps more than any other cell type, depend on mitochondrial trafficking for their
survival. Recent studies have elucidated a motor/adaptor complex on the mitochondrial …

Efficacy of human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine against cervical infection and precancer caused by oncogenic HPV types (PATRICIA): final …

J Paavonen, P Naud, J Salmerón, CM Wheeler… - The Lancet, 2009 - thelancet.com
Background The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine was
immunogenic, generally well tolerated, and effective against HPV-16 or HPV-18 infections …

[HTML][HTML] Respiratory syncytial virus prefusion F protein vaccine in older adults

A Papi, MG Ison, JM Langley, DG Lee… - … England Journal of …, 2023 - Mass Medical Soc
Background Respiratory syncytial virus (RSV) is an important cause of acute respiratory
infection, lower respiratory tract disease, clinical complications, and death in older adults …

[HTML][HTML] PINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motility

X Wang, D Winter, G Ashrafi, J Schlehe, YL Wong… - Cell, 2011 - cell.com
Cells keep their energy balance and avoid oxidative stress by regulating mitochondrial
movement, distribution, and clearance. We report here that two Parkinson's disease …

Safety, reactogenicity, and immunogenicity of homologous and heterologous prime-boost immunisation with ChAdOx1 nCoV-19 and BNT162b2: a prospective cohort …

D Hillus, T Schwarz, P Tober-Lau… - The Lancet …, 2021 - thelancet.com
Background Heterologous vaccine regimens have been widely discussed as a way to
mitigate intermittent supply shortages and to improve immunogenicity and safety of COVID …

Human keratinocytes are a source for tumor necrosis factor alpha: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light.

A Köck, T Schwarz, R Kirnbauer, A Urbanski… - The Journal of …, 1990 - rupress.org
Tumor necrosis factor alpha (TNF-alpha), in addition to being cytotoxic for certain tumor
cells, has turned out as a multifunctional cytokine that is involved in the regulation of …

[HTML][HTML] Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

T Usui, Y Shima, Y Shimada, S Hirano, RW Burgess… - Cell, 1999 - cell.com
We identified a seven-pass transmembrane receptor of the cadherin superfamily,
designated Flamingo (Fmi), localized at cell–cell boundaries in the Drosophila wing. In the …

Cloning of Genomic and Complementary DNA from Shaker, a Putative Potassium Channel Gene from Drosophila

DM Papazian, TL Schwarz, BL Tempel, YN Jan, LY Jan - Science, 1987 - science.org
On the basis of electrophysiological analysis of Shaker mutants, the Shaker locus of
Drosophila melanogaster has been proposed to encode a structural component of a voltage …