EULAR recommendations for terminology and research in individuals at risk of rheumatoid arthritis: report from the Study Group for Risk Factors for Rheumatoid …

DM Gerlag, K Raza, LGM Van Baarsen… - Annals of the …, 2012 - ard.bmj.com
The Study Group for Risk Factors for Rheumatoid Arthritis was established by the EULAR
Standing Committee on Investigative Rheumatology to facilitate research into the preclinical …

Persistent inflammatory and non-inflammatory mechanisms in refractory rheumatoid arthritis

MH Buch, S Eyre, D McGonagle - Nature Reviews Rheumatology, 2021 - nature.com
Despite nearly three decades of advances in the management of rheumatoid arthritis (RA), a
substantial minority of patients are exposed to multiple DMARDs without necessarily …

Genetics of rheumatoid arthritis: 2018 status

Y Okada, S Eyre, A Suzuki, Y Kochi… - Annals of the rheumatic …, 2019 - ard.bmj.com
Study of the genetics of rheumatoid arthritis (RA) began about four decades ago with the
discovery of HLA-DRB1. Since the beginning of this century, a number of non-HLA risk loci …

Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci

EA Stahl, S Raychaudhuri, EF Remmers, G Xie… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …

Dense genotyping of immune-related disease regions identifies 14 new susceptibility loci for juvenile idiopathic arthritis

A Hinks, J Cobb, MC Marion, S Prahalad, M Sudman… - Nature …, 2013 - nature.com
We used the Immunochip array to analyze 2,816 individuals with juvenile idiopathic arthritis
(JIA), comprising the most common subtypes (oligoarticular and rheumatoid factor–negative …

Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk

S Raychaudhuri, BP Thomson, EF Remmers, S Eyre… - Nature …, 2009 - nature.com
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P< 0.001 in a published meta-analysis of RA genome-wide …

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

K Ishigaki, S Sakaue, C Terao, Y Luo, K Sonehara… - Nature …, 2022 - nature.com
Rheumatoid arthritis (RA) is a highly heritable complex disease with unknown etiology. Multi-
ancestry genetic research of RA promises to improve power to detect genetic signals, fine …

Youth homelessness in San Francisco: A life cycle approach

CL Auerswald, SL Eyre - Social science & medicine, 2002 - Elsevier
HIV risk behaviors and seroprevalence are particularly high among street youth. Though
many programs have been designed to serve them, street youth have low rates of service …

Widespread non-additive and interaction effects within HLA loci modulate the risk of autoimmune diseases

TL Lenz, AJ Deutsch, B Han, X Hu, Y Okada, S Eyre… - Nature …, 2015 - nature.com
Human leukocyte antigen (HLA) genes confer substantial risk for autoimmune diseases on a
log-additive scale. Here we speculated that differences in autoantigen-binding repertoires …

[PDF][PDF] A large-scale genetic analysis reveals a strong contribution of the HLA class II region to giant cell arteritis susceptibility

FD Carmona, SL Mackie, JE Martín, JC Taylor… - The American Journal of …, 2015 - cell.com
We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic
immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with …