Risankizumab, an IL-23 inhibitor, for ankylosing spondylitis: results of a randomised, double-blind, placebo-controlled, proof-of-concept, dose-finding phase 2 study
D Baeten, M Østergaard, JCC Wei, J Sieper… - Annals of the …, 2018 - ard.bmj.com
Objectives To evaluate the efficacy and safety of risankizumab, a humanised monoclonal
antibody targeting the p19 subunit of interleukin-23 (IL-23), in patients with active ankylosing …
antibody targeting the p19 subunit of interleukin-23 (IL-23), in patients with active ankylosing …
Anti–IL-23A mAb BI 655066 for treatment of moderate-to-severe psoriasis: Safety, efficacy, pharmacokinetics, and biomarker results of a single-rising-dose …
JG Krueger, LK Ferris, A Menter, F Wagner… - Journal of Allergy and …, 2015 - Elsevier
Background IL-23 is associated with plaque psoriasis susceptibility and pathogenesis. BI
655066 is a fully human IgG 1 mAb specific for the IL-23 p19 subunit. Objective This first-in …
655066 is a fully human IgG 1 mAb specific for the IL-23 p19 subunit. Objective This first-in …
Effect of blood pressure during the acute period of ischemic stroke on stroke outcome: a tertiary analysis of the GAIN International Trial
S Aslanyan, F Fazekas, CJ Weir, S Horner, KR Lees - Stroke, 2003 - Am Heart Assoc
Background and Purpose—The effects of blood pressure (BP) and its fluctuations during the
acute phase on the clinical course of ischemic stroke are incompletely understood. We …
acute phase on the clinical course of ischemic stroke are incompletely understood. We …
Effect of area-based deprivation on the severity, subtype, and outcome of ischemic stroke
S Aslanyan, CJ Weir, KR Lees, JL Reid, GT McInnes - Stroke, 2003 - Am Heart Assoc
Background and Purpose—Markers of low socioeconomic status (deprivation) are
associated with stroke and its causes. In the United Kingdom, area-based deprivation …
associated with stroke and its causes. In the United Kingdom, area-based deprivation …
Magnesium for treatment of acute lacunar stroke syndromes: further analysis of the IMAGES trial
S Aslanyan, CJ Weir, KW Muir, KR Lees - Stroke, 2007 - Am Heart Assoc
Background and Purpose—A prespecified interaction analysis of the neutral Intravenous
Magnesium Efficacy in Stroke (IMAGES) trial revealed significant benefit from magnesium …
Magnesium Efficacy in Stroke (IMAGES) trial revealed significant benefit from magnesium …
Elevated pulse pressure during the acute period of ischemic stroke is associated with poor stroke outcome
S Aslanyan, CJ Weir, KR Lees - Stroke, 2004 - Am Heart Assoc
Background—It is controversial which component of blood pressure (BP) during acute
period of stroke best predicts outcome. We hypothesized that elevated pulse pressure (PP) …
period of stroke best predicts outcome. We hypothesized that elevated pulse pressure (PP) …
[HTML][HTML] Long-term efficacy and safety of risankizumab in patients with active psoriatic arthritis: results from a 76-week phase 2 randomized trial
PJ Mease, H Kellner, A Morita, AJ Kivitz… - Rheumatology and …, 2022 - Springer
Introduction The objective of this work was to assess the efficacy and safety of risankizumab
in psoriatic arthritis (PsA) over 76 weeks. Methods In this double-blind, dose-ranging phase …
in psoriatic arthritis (PsA) over 76 weeks. Methods In this double-blind, dose-ranging phase …
Poststroke neurological improvement within 7 days is associated with subsequent deterioration
S Aslanyan, CJ Weir, SC Johnston, KR Lees - Stroke, 2004 - Am Heart Assoc
Background and Purpose—Improvement in the National Institutes of Health Stroke Scale
(NIHSS) 24 hours after stroke has been associated with subsequent neurological …
(NIHSS) 24 hours after stroke has been associated with subsequent neurological …
Effects of tipranavir, darunavir, and ritonavir on platelet function, coagulation, and fibrinolysis in healthy volunteers
JJ Kort, S Aslanyan, J Scherer, JP Sabo… - Current HIV …, 2011 - ingentaconnect.com
The use of HIV protease inhibitors (PIs) as part of antiretroviral therapy in the treatment of
HIV-1 infection may be associated with an increased risk of bleeding. This prospective …
HIV-1 infection may be associated with an increased risk of bleeding. This prospective …
HCVerso1 and 2: faldaprevir with deleobuvir (BI 207127) and ribavirin for treatment-naïve patients with chronic hepatitis C virus genotype-1b infection
The interferon-free combination of once-daily faldaprevir 120 mg, twice-daily deleobuvir 600
mg, and weight-based ribavirin was evaluated in two Phase III studies (HCVerso1 …
mg, and weight-based ribavirin was evaluated in two Phase III studies (HCVerso1 …