[HTML][HTML] Association of Systemic Lupus Erythematosus with C8orf13–BLK and ITGAM–ITGAX
G Hom, RR Graham, B Modrek, KE Taylor… - … England Journal of …, 2008 - Mass Medical Soc
Background Systemic lupus erythematosus (SLE) is a clinically heterogeneous disease in
which the risk of disease is influenced by complex genetic and environmental contributions …
which the risk of disease is influenced by complex genetic and environmental contributions …
A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of …
S Sigurdsson, G Nordmark, S Garnier… - Human molecular …, 2008 - academic.oup.com
Systemic lupus erythematosus (SLE) is the prototype autoimmune disease where genes
regulated by type I interferon (IFN) are over-expressed and contribute to the disease …
regulated by type I interferon (IFN) are over-expressed and contribute to the disease …
[HTML][HTML] Exome-wide association study reveals novel susceptibility genes to sporadic dilated cardiomyopathy
U Esslinger, S Garnier, A Korniat, C Proust… - PLoS …, 2017 - journals.plos.org
Aims Dilated cardiomyopathy (DCM) is an important cause of heart failure with a strong
familial component. We performed an exome-wide array-based association study (EWAS) to …
familial component. We performed an exome-wide array-based association study (EWAS) to …
A STAT4 risk allele is associated with ischaemic cerebrovascular events and anti-phospholipid antibodies in systemic lupus erythematosus
E Svenungsson, J Gustafsson, D Leonard… - Annals of the …, 2010 - ard.bmj.com
Objective To investigate whether the risk allele for systemic lupus erythematosus (SLE) in
the signal transducer and activator of transcription factor 4 (STAT4) gene, defined by the …
the signal transducer and activator of transcription factor 4 (STAT4) gene, defined by the …
Linkage proof for PTPN22, a rheumatoid arthritis susceptibility gene and a human autoimmunity gene
L Michou, S Lasbleiz, AC Rat… - Proceedings of the …, 2007 - National Acad Sciences
The tyrosine phosphatase PTPN22 allele 1858T has been associated with rheumatoid
arthritis (RA) and other autoimmune diseases. RA is the most frequent of those multifactorial …
arthritis (RA) and other autoimmune diseases. RA is the most frequent of those multifactorial …
Genome-wide association analysis in dilated cardiomyopathy reveals two new players in systolic heart failure on chromosomes 3p25. 1 and 22q11. 23
S Garnier, M Harakalova, S Weiss, M Mokry… - European heart …, 2021 - academic.oup.com
Aims Our objective was to better understand the genetic bases of dilated cardiomyopathy
(DCM), a leading cause of systolic heart failure. Methods and results We conducted the …
(DCM), a leading cause of systolic heart failure. Methods and results We conducted the …
[HTML][HTML] A candidate gene study of the type I interferon pathway implicates IKBKE and IL8 as risk loci for SLE
JK Sandling, S Garnier, S Sigurdsson… - European Journal of …, 2011 - nature.com
Abstract Systemic Lupus Erythematosus (SLE) is a systemic autoimmune disease in which
the type I interferon pathway has a crucial role. We have previously shown that three genes …
the type I interferon pathway has a crucial role. We have previously shown that three genes …
[HTML][HTML] Genome-Wide Haplotype Analysis of Cis Expression Quantitative Trait Loci in Monocytes
S Garnier, V Truong, J Brocheton, T Zeller… - PLoS …, 2013 - journals.plos.org
In order to assess whether gene expression variability could be influenced by several SNPs
acting in cis, either through additive or more complex haplotype effects, a systematic …
acting in cis, either through additive or more complex haplotype effects, a systematic …
Influence of a walking program on the metabolic risk profile of obese postmenopausal women
M Roussel, S Garnier, S Lemoine, I Gaubert… - Menopause, 2009 - journals.lww.com
Objective: Menopause transition is associated with an increased prevalence of metabolic
syndrome (MS), which may partly explain the higher coronary heart disease risk. The aim of …
syndrome (MS), which may partly explain the higher coronary heart disease risk. The aim of …
[HTML][HTML] Genetic architecture of spatial electrical biomarkers for cardiac arrhythmia and relationship with cardiovascular disease
Abstract The 3-dimensional spatial and 2-dimensional frontal QRS-T angles are measures
derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but …
derived from the vectorcardiogram. They are independent risk predictors for arrhythmia, but …