Precision medicine is part of the logical evolution of contemporary evidence-based medicine
that seeks to reduce errors and optimize outcomes when making medical decisions and …

Background Rheumatoid arthritis (RA) considerably impacts patients' mental health.
However, it is largely unclear how people suffering from RA experience psychological stress …

Objectives Although eHealth tools are potentially useful for remote disease monitoring,
barriers include concerns of low engagement and high attrition. We aimed to summarise …

Objectives To investigate whether MTX should be combined with an additional DMARD and
bridging glucocorticoids as initial treatment for patients with early RA to induce an effective …

Objective This study investigated how psychosocial aspects of disease affect the probability
of achieving sustained remission in early rheumatoid arthritis (RA) and explored the …

Objectives In osteoarthritis, methylation of lysine 79 on histone H3 (H3K79me), a protective
epigenetic mechanism, is reduced. Histone methylation levels are dynamically regulated by …

Background Shifts in treatment strategies for rheumatoid arthritis (RA) have made
ambulatory care more labour-intensive. These developments have prompted innovative …

Objectives To compare outcomes of different treatment schedules from the care in early
rheumatoid arthritis (CareRA) trial over 5 years. Methods Patients with RA completing the 2 …

Objective Fatigue is common in rheumatoid arthritis (RA). We aimed to explore its
longitudinal course, predictors and association with disease activity in early RA. Methods …

Objectives To identify and characterise a subgroup of patients with early rheumatoid arthritis
(RA) reporting not feeling well 1 year after treatment initiation despite achieving optimal …