Abstract tRNAs, nexus molecules between mRNAs and proteins, have a central role in
translation. Recent discoveries have revealed unprecedented complexity of tRNA …

Computational tools for predicting toxicity have been envisaged for their potential to
considerably impact the attrition rate of compounds in drug discovery and development. In …

Background There is strong evidence that suicides increase after media stories about
suicides by celebrities, particularly those that highlight the suicide method (the Werther …

At the Washington “2nd International Workshop on Genotoxicity Testing”(25–26 March
1999) current methodologies and data for the in vitro micronucleus test were reviewed. As a …

Workshop participants agreed that genotoxicity tests in mammalian cells in vitro produce a
remarkably high and unacceptable occurrence of irrelevant positive results (eg when …

The environmental obesogen hypothesis proposes that pre-and postnatal exposure to
environmental chemicals contributes to adipogenesis and the development of obesity …

The origin of unconventional superconductivity, including high-temperature and heavy-
fermion superconductivity, is still a matter of controversy. Spin excitations instead of phonons …

Two cDNA clones with homology to known desaturase genes were isolated from the fungus
Mortierella alpina. The open reading frame in one clone encoded 399 amino acids and …

A DNA fragment with homology to Δ6-desaturases from borage and cyanobacteria was
isolated after polymerase chain reaction amplification of Mortierella alpina cDNA with …

In glycomethacrylate sections of sun-exposed skin, we found the epidermis a sensitive index
of damage. The stratum corneum of severely damaged skin was often compact and …