Efficacy and safety of abatacept or infliximab vs placebo in ATTEST: a phase III, multi-centre, randomised, double-blind, placebo-controlled study in patients with …

…, S Songcharoen, A Berman, S Nayiager… - Annals of the …, 2008 - ard.bmj.com
Objectives: This double-blind trial evaluated the efficacy and safety of abatacept or infliximab
vs placebo. The primary objective of this study was to evaluate the mean change from …

Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients with rheumatoid arthritis (ORAL Strategy): a …

…, L Adams, MM Ally, MC du Plooy, IC Louw, S Nayiager… - The Lancet, 2017 - thelancet.com
Background Tofacitinib is an oral Janus kinase inhibitor for the treatment of rheumatoid
arthritis. The Oral Rheumatoid Arthritis triaL (ORAL) Strategy aimed to assess the …

Clinical efficacy and safety of abatacept in methotrexate-naive patients with early rheumatoid arthritis and poor prognostic factors

…, M Robles, AC Ximenes, S Nayiager… - Annals of the …, 2009 - ard.bmj.com
Objectives: To assess the efficacy and safety of abatacept in methotrexate-naive patients
with early rheumatoid arthritis (RA) and poor prognostic factors. Methods: In this double …

Sustained disease remission and inhibition of radiographic progression in methotrexate-naive patients with rheumatoid arthritis and poor prognostic factors treated …

J Bathon, M Robles, AC Ximenes, S Nayiager… - Annals of the …, 2011 - ard.bmj.com
Objective To assess the efficacy and safety of abatacept plus methotrexate versus
methotrexate alone in early erosive rheumatoid arthritis (RA). Methods The AGREE was a 2 …

Autonomic nervous system dysfunction in severe tetanus: current perspectives

DK WRIGHT, UG LALLOO, S NAYIAGER… - Critical care …, 1989 - journals.lww.com
The enigma of autonomic nervous system dysfunction in severe tetanus is discussed in the
light of recent and older evidence concerning the nature and action of tetanus toxin, its …

Immunogenicity, safety, and efficacy of abatacept administered subcutaneously with or without background methotrexate in patients with rheumatoid arthritis: results …

P Nash, S Nayiager, MC Genovese… - Arthritis care & …, 2013 - Wiley Online Library
Objective To evaluate the impact of concomitant methotrexate (MTX) on subcutaneous (SC)
abatacept immunogenicity, and to assess safety and efficacy. Methods This phase III, open …

Clinical response and tolerability to abatacept in patients with rheumatoid arthritis previously treated with infliximab or abatacept: open-label extension of the ATTEST …

…, S Songcharoen, A Berman, S Nayiager… - Annals of the …, 2011 - ard.bmj.com
Objective To assess the efficacy and safety of abatacept in biological-naive patients with
rheumatoid arthritis and an inadequate response to methotrexate treated in the long-term …

Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritis

AJ Kivitz, S Nayiager, T Schimansky… - Alimentary …, 2004 - Wiley Online Library
Summary Background: Lumiracoxib (Prexige; Novartis Pharma AG, Basel, Switzerland) is a
cyclooxygenase‐2 selective inhibitor associated with improved gastrointestinal safety …

Lack of association of Human T-cell lymphotrophic virus type 1 (HTLV-1) infection and rheumatoid arthritis in an endemic area

D Sebastian, S Nayiager, DY York, GM Mody - Clinical rheumatology, 2003 - Springer
Abstract In South Africa the association of HTLV-1 infection with myelopathy is well
described in Kwa Zulu Natal, which is an endemic area for HTLV-1 infection. Japan also has …

[CITATION][C] ORAL Strategy investigators. Efficacy and safety of tofacitinib monotherapy, tofacitinib with methotrexate, and adalimumab with methotrexate in patients …

…, L Adams, MM Ally, MC Du Plooy, IC Louw, S Nayiager… - Lancet, 2017