From randomized controlled trials to observational studies
SL Silverman - The American journal of medicine, 2009 - Elsevier
Randomized controlled trials are considered the gold standard in the hierarchy of research
designs for evaluating the efficacy and safety of a treatment intervention. However, their …
designs for evaluating the efficacy and safety of a treatment intervention. However, their …
A systematic review of persistence and compliance with bisphosphonates for osteoporosis
JA Cramer, DT Gold, SL Silverman… - Osteoporosis …, 2007 - Springer
Fourteen reports utilizing data from de-identified administrative databases were reviewed.
Studies contained at least one measure of patient persistence or compliance with …
Studies contained at least one measure of patient persistence or compliance with …
Impact of osteoporosis treatment adherence on fracture rates in North America and Europe
ES Siris, PL Selby, KG Saag, F Borgström… - The American journal of …, 2009 - Elsevier
Fragility fractures associated with osteoporosis constitute a significant public health concern.
Clinical trials have shown that a variety of agents—bisphosphonates, raloxifene, calcitonin …
Clinical trials have shown that a variety of agents—bisphosphonates, raloxifene, calcitonin …
Bisphosphonate‐associated osteonecrosis of the jaw: report of a task force of the American Society for Bone and Mineral Research
ONJ has been increasingly suspected to be a potential complication of bisphosphonate
therapy in recent years. Thus, the ASBMR leadership appointed a multidisciplinary task …
therapy in recent years. Thus, the ASBMR leadership appointed a multidisciplinary task …
Risk of new vertebral fracture in the year following a fracture
R Lindsay, SL Silverman, C Cooper, DA Hanley… - Jama, 2001 - jamanetwork.com
ContextVertebral fractures significantly increase lifetime risk of future fractures, but risk of
further vertebral fractures in the period immediately following a vertebral fracture has not …
further vertebral fractures in the period immediately following a vertebral fracture has not …
Fractures attributable to osteoporosis: report from the National Osteoporosis Foundation
LJ Melton III, M Thamer, NF Ray… - Journal of Bone and …, 1997 - academic.oup.com
To assess the cost‐effectiveness of interventions to prevent osteoporosis, it is necessary to
estimate total health care expenditures for the treatment of osteoporotic fractures. Resources …
estimate total health care expenditures for the treatment of osteoporotic fractures. Resources …
Comparison of sulfasalazine and placebo in the treatment of psoriatic arthritis. A Department of Veterans Affairs Cooperative Study
Objective. To determine whether sulfasalazine (SSZ) at a dosage of 2,000 mg/day is
effective for the treatment of active psoriatic arthritis (PsA) resistant to nonsteroidal …
effective for the treatment of active psoriatic arthritis (PsA) resistant to nonsteroidal …
Efficacy of bazedoxifene in reducing new vertebral fracture risk in postmenopausal women with osteoporosis: results from a 3‐year, randomized, placebo‐, and active …
SL Silverman, C Christiansen… - Journal of bone and …, 2008 - academic.oup.com
Abstract In this 3‐yr, randomized, double‐blind, placebo‐and active‐controlled study,
healthy postmenopausal women with osteoporosis (55–85 yr of age) were treated with …
healthy postmenopausal women with osteoporosis (55–85 yr of age) were treated with …
Incidence of atypical nontraumatic diaphyseal fractures of the femur
Bisphosphonates reduce the rate of osteoporotic fractures in clinical trials and community
practice.“Atypical” nontraumatic fractures of the diaphyseal (subtrochanteric or shaft) part of …
practice.“Atypical” nontraumatic fractures of the diaphyseal (subtrochanteric or shaft) part of …
Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2 year results from the MOBILE study
JY Reginster, S Adami, P Lakatos… - Annals of the …, 2006 - ard.bmj.com
Background: Reducing bisphosphonate dosing frequency may improve suboptimal
adherence to treatment and therefore therapeutic outcomes in postmenopausal …
adherence to treatment and therefore therapeutic outcomes in postmenopausal …