Differential proteome analysis is used to study body fluids from patients suffering from
rheumatoid arthritis (RA), reactive arthritis (reaA) or osteoarthritis (OA). Mass spectrometric …

Introduction About 30% of rheumatoid arthritis patients fail to respond adequately to TNFα-
blocking therapy. There is a medical and socioeconomic need to identify molecular markers …

To date, mesenchymal cells have only been associated with bone resorption indirectly, and
it has been hypothesized that the degradation of bone is associated exclusively with specific …

Several indicators reflect the quality of care within emergency departments (ED). The length
of stay (LOS) of emergency patients represents one of the most important performance …

Background Signs and symptoms establish the diagnosis of adult onset Still's disease
(AOSD) as well as of systemic onset juvenile idiopathic arthritis (sJIA). The published data …

Background Rheumatoid arthritis (RA) and juvenile rheumatoid arthritis (JRA) are complex
multifactorial diseases caused by environmental influences and an unknown number of …

New experimental approaches of molecular medicine such as transcriptome and proteome
analysis have been implemented in rheumatology research. Two-dimensional gel …

Objectives: To analyse the association of interleukin 10 (IL10) promoter polymorphisms,
which have been shown to be related to IL10 secretion capacity, with the response to long …

Background: Rheumatoid arthritis (RA) is a systemic autoimmune disease in which synovial
fibroblasts (SF) play a key role. Baricitinib and Tofacitinib both act intracellularly, blocking …

The balance of bone formation and resorption is the result of a regulated crosstalk between
osteoblasts, osteoclasts, and osteocytes. Inflammation, mechanical load, and external …