Objectives Autophagy has recently been shown to regulate osteoclast activity and osteoclast
differentiation. Here, we aim to investigate the impact of autophagy inhibition as a potential …

Abstract Interleukin (IL)‐27, a newly discovered IL‐12 family cytokine, is composed of p28
and EBI3. In this study, CD11c‐p28f/f conditional knockout mice were generated to delete …

Con A-induced fulminant hepatitis is a well-known animal model for acute liver failure.
However, the role of γδ T cells in this model is undefined. In this report, using TCR δ …

Objectives Systemic sclerosis (SSc) fibroblasts remain activated even in the absence of
exogenous stimuli. Epigenetic alterations are thought to play a role for this endogenous …

Bioactive glass nanoparticles containing copper (Cu-BGNs) were introduced into
polycaprolactone (PCL) coating systems to improve the bioactivity, antibacterial properties …

Objectives Janus kinase 2 (JAK2) has recently been described as a novel downstream
mediator of the pro-fibrotic effects of transforming growth factor-β. Although JAK2 inhibitors …

Objectives Hedgehog signalling plays a critical role during the pathogenesis of fibrosis in
systemic sclerosis (SSc). Besides canonical hedgehog signalling with smoothened (SMO) …

Bone mass is maintained by the balance between osteoclast-induced bone resorption and
osteoblast-triggered bone formation. In inflammatory arthritis such as rheumatoid arthritis …

Objectives The enzyme poly (ADP-ribose) polymerase-1 (PARP-1) transfers negatively
charged ADP-ribose units to target proteins. This modification can have pronounced …

Novel branch-trunk Ag hierarchical nanostructures were fabricated by hydrothermal process
combined with microwave-assisted synthesis. Te nanowires prepared by hydrothermal …