The Wnt antagonists DKK1 and SFRP1 are downregulated by promoter hypermethylation in systemic sclerosis

C Dees, I Schlottmann, R Funke, A Distler… - Annals of the …, 2014 - ard.bmj.com
Objectives Activated Wnt signalling with decreased expression of endogenous inhibitors has
recently been characterised as a central pathomechanism in systemic sclerosis (SSc) …

Epigenetic silencing of endogenous inhibitors of the WNT-pathway caused by promoter methylation in Systemic Sclerosis

R Funke - open.fau.de
1. Objective Systemic sclerosis (SSc) is a rare connective tissue disease belonging to the
family of autoimmune diseases. As its clinical appearance may vary, the SSc is …

Epigenetisches Silencing von endogenen Inhibitoren des WNT-Signalweges durch Promoter Methylierung in der Systemischen Sklerose

R Funke - 2012 - opus4.kobv.de
1. Hintergrund und Ziele Die Systemische Sklerose (SSc) ist eine seltene Erkrankung des
Bindegewebes und gehört zur Familie der Autoimmunkrankheiten. Die SSc zeigt eine starke …

[CITATION][C] The Wnt Inhibitors DKK1 and SFRP1 Are Downregulated by Promoter Hypermethylation in Systemic Sclerosis

C Dees, I Schlottmann, R Funke… - ARTHRITIS …, 2012 - … ST, HOBOKEN 07030-5774, NJ USA