Redox catalysis in organic electrosynthesis: basic principles and recent developments

R Francke, RD Little - Chemical Society Reviews, 2014 - pubs.rsc.org
Electroorganic synthesis has become an established, useful, and environmentally benign
alternative to classic organic synthesis for the oxidation or the reduction of organic …

Organic electrosynthesis: a promising green methodology in organic chemistry

BA Frontana-Uribe, RD Little, JG Ibanez, A Palma… - Green …, 2010 - pubs.rsc.org
Over the last decade, organic electrosynthesis has become recognized as one of the
methodologies that can fulfill several important criteria that are needed if society is to …

The odyssey of marine pharmaceuticals: a current pipeline perspective

…, C Cuevas, RS Jacobs, W Kem, RD Little… - Trends in …, 2010 - cell.com
The global marine pharmaceutical pipeline consists of three Food and Drug Administration
(FDA) approved drugs, one EU registered drug, 13 natural products (or derivatives thereof) …

Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness

P Van Eerdewegh, RD Little, J Dupuis, RG Del Mastro… - Nature, 2002 - nature.com
Asthma is a common respiratory disorder characterized by recurrent episodes of coughing,
wheezing and breathlessness. Although environmental factors such as allergen exposure …

[PDF][PDF] A mutation in the LDL receptor–related protein 5 gene results in the autosomal dominant high–bone-mass trait

RD Little, C Folz, SP Manning, PM Swain… - The American Journal of …, 2002 - cell.com
Osteoporosis is a complex disease that affects> 10 million people in the United States and
results in 1.5 million fractures annually. In addition, the high prevalence of osteopenia (low …

An exceptionally simple and efficient method for the preparation of a wide variety of fulvenes

KJ Stone, RD Little - The Journal of Organic Chemistry, 1984 - ACS Publications
A simple high yield method for the preparation of a wide range of structurally diverse
fulvenes is described. Pyrrolidine proves to be a very effective reagent to promote fulvene …

Three newly isolated plant growth-promoting bacilli facilitate the seedling growth of canola, Brassica campestris

S Ghosh, JN Penterman, RD Little, R Chavez… - Plant Physiology and …, 2003 - Elsevier
Three strains of plant growth-promoting bacteria were isolated from southeastern Wisconsin
soils, based upon the ability to utilize the compound 1-aminocyclopropane-1-carboxylic acid …

Versatile tools for understanding electrosynthetic mechanisms

…, BHR Gerroll, MS Mubarak, LA Baker, RD Little - Chemical …, 2021 - ACS Publications
Electrosynthesis is a popular, green alternative to traditional organic methods.
Understanding the mechanisms is not trivial yet is necessary to optimize reaction processes …

The Intramolecular M ichael Reaction

RD Little, MR Masjedizadeh, O Wallquist… - Organic …, 2004 - Wiley Online Library
Like its intermolecular counterpart, the intramolecular Michael reaction involves the addition
of a nucleophile, often referred to as the donor, to an acceptor, usually an olefin bearing one …

Initiation and termination of DNA replication in human rRNA genes

RD Little, THK Platt, CL Schildkraut - Molecular and cellular …, 1993 - Am Soc Microbiol
We have used the multicopy human rRNA genes as a model system to study replication
initiation and termination in mammalian chromosomes. Enrichment for replicating molecules …