The German etanercept registry for treatment of juvenile idiopathic arthritis

…, T Hospach, HI Huppertz, R Keitzer… - Annals of the …, 2004 - ard.bmj.com
Objective: To describe a registry set up to monitor children treated with etanercept in
Germany and Austria. Methods: Giannini's criteria, duration of morning stiffness, number of …

Colchicine use in children and adolescents with familial Mediterranean fever: literature review and consensus statement

…, C Schaefer, S Stojanov, C Timmann, R Keitzer… - …, 2007 - publications.aap.org
The daily application of colchicine is the standard therapy for prophylaxis of attacks and
amyloid deposition in familial Mediterranean fever. However, because of many issues (eg …

Takayasu arteritis is characterised by disturbances of B cell homeostasis and responds to B cell depletion therapy with rituximab

…, C Sengler, KG Hermann, S Maza, R Keitzer… - Annals of the …, 2012 - ard.bmj.com
Introduction Takayasu arteritis (TA) is a large vessel vasculitis involving the aorta and its
major branches. T cell-mediated autoimmunity is thought to play a major role in its …

Neutrophil-derived S100A12 as novel biomarker of inflammation in familial Mediterranean fever

T Kallinich, H Wittkowski, R Keitzer, J Roth… - Annals of the rheumatic …, 2010 - ard.bmj.com
Objective Familial Mediterranean fever (FMF) is characterised by recurrent periodic febrile
attacks and persistent subclinical inflammation. The damage-associated molecular pattern …

Perturbations of peripheral B lymphocyte homoeostasis in children with systemic lupus erythematosus

M Odendahl, R Keitzer, U Wahn, F Hiepe… - Annals of the …, 2003 - ard.bmj.com
Objective: To investigate the distribution of peripheral B cell subpopulations of children with
active and inactive systemic lupus erythematosus (SLE) compared with healthy controls …

Association study of polymorphisms within interleukin‐18 in juvenile idiopathic arthritis and bronchial asthma

…, K Ganter, T Kurz, L Schuchmann, R Keitzer… - Allergy, 2004 - Wiley Online Library
Background: Interleukin‐18 (IL‐18) plays an important role in the regulation of TH1 as well
as TH2 immunologic responses and thus in the development of chronic inflammatory …

Acute rheumatic fever (ARF) and poststreptococcal reactive arthritis (PSRA)—an update: Ein Update

R Keitzer - Zeitschrift für Rheumatologie, 2005 - Springer
Betahemolytic strains of streptococcus A are able to induce a spectrum of immunologically
induced diseases, depending on the immunogenic M structure of the bacteria as well as on …

De novo terminal deletion of chromosome 15q26. 1 characterised by comparative genomic hybridisation and FISH with locus specific probes

…, HC Hennies, LM Neumann, R Keitzer… - Journal of medical …, 2001 - jmg.bmj.com
Results A group of 40 patients, 27 with autosomal dominant macular dystrophy and 13 with
autosomal dominant cone or cone-rod dystrophy, was screened for mutations in all exons of …

[HTML][HTML] Effect of glucocorticoid therapy on glucocorticoid receptors in children with autoimmune diseases

…, R Tripmacher, R Weltrich, W Rohde, R Keitzer… - Pediatric …, 2001 - nature.com
Low-dose glucocorticoids (GC) achieve their action completely by classical genomic effects,
mediated by the glucocorticoid receptor (GCR). In high doses of GC, nongenomic effects …

“Periodic fever” without fever: two cases of non-febrile TRAPS with mutations in the TNFRSF1A gene presenting with episodes of inflammation or monosymptomatic …

…, R Schindler, S Canaan-Kühl, R Keitzer… - Annals of the …, 2006 - ard.bmj.com
Background: Tumour necrosis factor (TNF) receptor associated periodic syndrome (TRAPS)
is caused by dominant mutations in the TNFRSF1A gene. In typical cases TRAPS begins …