Ultraviolet A (UVA) radiation represents more than 90% of the solar UV radiation reaching
Earth's surface. Exposure to solar UV radiation is a major risk in the occurrence of non …

With the introduction of more efficient treatments for hepatitis C virus (HCV), improved
epidemiological information is required at the country level to allow evidence‐based …

Although nephrotoxicity of cidofovir and adefovir is well established, no renal side effects
have been observed yet with tenofovir, which is the third member of this family. The authors …

Background Lipodystrophy is a major side-effect of antiretroviral therapy but its
pathophysiology remains elusive. In-vitro studies show that HIV-1-protease inhibitors affect …

In response to ionizing radiation (IR), the tumor suppressor p53 is stabilized and promotes
either cell cycle arrest or apoptosis. Chk2 activated by IR contributes to this stabilization …

Background Effective two-drug regimens could decrease long-term drug exposure and
toxicity with HIV-1 antiretroviral therapy (ART). We therefore aimed to evaluate the efficacy …

Background Lifelong HIV antiretroviral therapy (ART) has prompted an interest in two-drug
regimens to minimise cumulative drug exposure and toxicities. The safety, tolerability, and …

Cold atmospheric pressure plasmas (CAPPs) have emerged over the last decade as a new
promising therapy to fight cancer. CAPPs' antitumor activity is primarily due to the delivery of …

Background Integrase strand transfer inhibitors (INSTIs) are recommended components of
initial antiretroviral therapy with two nucleoside reverse transcriptase inhibitors. Bictegravir is …

Background Antiretroviral regimens containing tenofovir disoproxil fumarate have been
associated with renal toxicity and reduced bone mineral density. Tenofovir alafenamide is a …