Churg–Strauss syndrome

C Pagnoux, P Guilpain, L Guillevin - Current opinion in …, 2007 - journals.lww.com
The precise pathogenetic mechanisms of Churg–Strauss syndrome are only partly
elucidated. Recent results suggest that antineutrophil cytoplasmic autoantibodies are …

Alpha-enolase: a target of antibodies in infectious and autoimmune diseases

B Terrier, N Degand, P Guilpain, A Servettaz… - Autoimmunity …, 2007 - Elsevier
Alpha-enolase, also called non-neuronal enolase, belongs to a family of cytoplasmic and
glycolytic enzymes. In addition to its glycolytic function, alpha-enolase exerts many other …

Adult onset Still's disease (AOSD) in the era of biologic therapies: dichotomous view for cytokine and clinical expressions

ATJ Maria, A Le Quellec, C Jorgensen, I Touitou… - Autoimmunity …, 2014 - Elsevier
Adult onset Still's disease (AOSD) is a rare inflammatory disorder characterized by hectic
spiking fever, evanescent rash and joint involvement. Prognosis is highly variable upon …

Eosinophilic granulomatosis with polyangiitis (Churg‐Strauss): clinical characteristics and long‐term followup of the 383 patients enrolled in the French Vasculitis …

C Comarmond, C Pagnoux, M Khellaf… - Arthritis & …, 2013 - Wiley Online Library
Objective Earlier studies of eosinophilic granulomatosis with polyangiitis (Churg‐
Strauss)(EGPA), with limited patient numbers and followup durations, demonstrated that …

Selective oxidation of DNA topoisomerase 1 induces systemic sclerosis in the mouse

A Servettaz, C Goulvestre, N Kavian… - The Journal of …, 2009 - journals.aai.org
Systemic sclerosis (SSc) is a connective tissue disorder of great clinical heterogeneity. Its
pathophysiology remains unclear. Our aim was to evaluate the relative roles of reactive …

Rituximab for granulomatosis with polyangiitis in the pandemic of covid-19: lessons from a case with severe pneumonia

P Guilpain, C Le Bihan, V Foulongne… - Annals of the …, 2021 - ard.bmj.com
In the pandemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) disease
2019 (covid-19), 1 2 the preliminary experience reported by Monti S and colleagues 3 …

Impact of digital ulcers on disability and health-related quality of life in systemic sclerosis

L Mouthon, C Mestre-Stanislas, A Bérezné… - Annals of the …, 2010 - ard.bmj.com
Objective: To assess the impact of digital ulcers (DUs) on disability and health-related
quality of life (HRQoL) in systemic sclerosis (SSc). Methods: Two hundred and thirteen …

Antibodies to fibroblasts in idiopathic and scleroderma-associated pulmonary hypertension

MC Tamby, M Humbert, P Guilpain… - European …, 2006 - Eur Respiratory Soc
The aim of the present study was to investigate the presence of anti-fibroblast antibodies in
patients with idiopathic or scleroderma-associated pulmonary arterial hypertension (PAH) …

Adipose-derived mesenchymal stem cells in autoimmune disorders: state of the art and perspectives for systemic sclerosis

ATJ Maria, M Maumus, A Le Quellec… - Clinical reviews in …, 2017 - Springer
Mesenchymal stromal/stem cells (MSC) are non-hematopoietic multipotent progenitor cells,
first described in bone marrow in the middle of last century. Since then, MSC have been the …

Human adipose mesenchymal stem cells as potent anti-fibrosis therapy for systemic sclerosis

ATJ Maria, K Toupet, M Maumus, G Fonteneau… - Journal of …, 2016 - Elsevier
Objectives Displaying immunosuppressive and trophic properties, mesenchymal
stem/stromal cells (MSC) are being evaluated as promising therapeutic options in a variety …