Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus
…, JL Nelson, SK Agarwal, S Assassi, P Gourh… - Nature …, 2010 - nature.com
Systemic sclerosis (SSc) is an autoimmune disease characterized by fibrosis of the skin and
internal organs that leads to profound disability and premature death. To identify new SSc …
internal organs that leads to profound disability and premature death. To identify new SSc …
Signatures of differentially regulated interferon gene expression and vasculotrophism in the peripheral blood cells of systemic sclerosis patients
FK Tan, X Zhou, MD Mayes, P Gourh, X Guo… - …, 2006 - academic.oup.com
Objective. To obtain a global view of the immunological alterations occurring in early
systemic sclerosis (SSc) by transcriptional profiling of peripheral blood cells (PBCs) …
systemic sclerosis (SSc) by transcriptional profiling of peripheral blood cells (PBCs) …
[HTML][HTML] Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy
…, J Varga, M Hinchcliff, AT Lee, P Gourh… - PLoS …, 2011 - journals.plos.org
The aim of this study was to determine, through a genome-wide association study (GWAS),
the genetic components contributing to different clinical sub-phenotypes of systemic …
the genetic components contributing to different clinical sub-phenotypes of systemic …
Major histocompatibility complex (MHC) class II alleles, haplotypes and epitopes which confer susceptibility or protection in systemic sclerosis: analyses in 1300 …
FC Arnett, P Gourh, S Shete, CW Ahn… - Annals of the …, 2010 - ard.bmj.com
Objective To determine human leucocyte antigen-class II (HLA-class II)(DRB1, DQB1, DQA1
and DPB1) alleles, haplotypes and shared epitopes associated with scleroderma (systemic …
and DPB1) alleles, haplotypes and shared epitopes associated with scleroderma (systemic …
Systemic sclerosis and lupus: points in an interferon‐mediated continuum
…, MD Mayes, FC Arnett, P Gourh… - … : Official Journal of …, 2010 - Wiley Online Library
Objective To investigate peripheral blood (PB) cell transcript profiles of systemic sclerosis
(SSc) and its subtypes in direct comparison with systemic lupus erythematosus (SLE) …
(SSc) and its subtypes in direct comparison with systemic lupus erythematosus (SLE) …
[HTML][HTML] Plasma cytokine profiles in systemic sclerosis: associations with autoantibody subsets and clinical manifestations
P Gourh, FC Arnett, S Assassi, FK Tan, M Huang… - Arthritis research & …, 2009 - Springer
Abstract Introduction Systemic sclerosis (SSc)(scleroderma) is a complex autoimmune
disease that clinically manifests as progressive fibrosis of the skin and internal organs. Anti …
disease that clinically manifests as progressive fibrosis of the skin and internal organs. Anti …
Clinical and genetic factors predictive of mortality in early systemic sclerosis
…, JD Reveille, A Karnavas, P Gourh… - Arthritis Care & …, 2009 - Wiley Online Library
Objective To investigate the clinical and genetic variables at initial presentation that predict
survival in the Genetics versus Environment in Scleroderma Outcome Study (GENISOS) …
survival in the Genetics versus Environment in Scleroderma Outcome Study (GENISOS) …
Association of the C8orf13-BLK region with systemic sclerosis in North-American and European populations
P Gourh, SK Agarwal, E Martin, D Divecha… - Journal of …, 2010 - Elsevier
OBJECTIVE: Genetic studies in the systemic sclerosis (SSc), an autoimmune disease that
clinically manifests with dermal and internal organ fibrosis and small vessel vasculopathy …
clinically manifests with dermal and internal organ fibrosis and small vessel vasculopathy …
Primary biliary cirrhosis (PBC), PBC autoantibodies, and hepatic parameter abnormalities in a large population of systemic sclerosis patients
Objective. To investigate the diagnostic accuracy of antimitochondrial antibodies (AMA),
sp100, and gp210 antibodies for primary biliary cirrhosis (PBC) in a large population of …
sp100, and gp210 antibodies for primary biliary cirrhosis (PBC) in a large population of …
BANK1 functional variants are associated with susceptibility to diffuse systemic sclerosis in Caucasians
B Rueda, P Gourh, J Broen, SK Agarwal… - Annals of the …, 2010 - ard.bmj.com
Objective To investigate the possible association of the BANK1 gene with genetic
susceptibility to systemic sclerosis (SSc) and its subphenotypes. Methods A large …
susceptibility to systemic sclerosis (SSc) and its subphenotypes. Methods A large …