Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening thrombotic
microangiopathy characterized by microangiopathic hemolytic anemia, severe …

Thrombotic thrombocytopenic purpura (TTP; also known as Moschcowitz disease) is
characterized by the concomitant occurrence of often severe thrombocytopenia …

Pregnancy and postpartum are high-risk periods for different forms of thrombotic
microangiopathy (TMA). However, the management of pregnancy-associated TMA remains …

Objective Because it has no unique clinical, biologic, or histologic features, reactive
hemophagocytic syndrome may be difficult to distinguish from other diseases such as …

Background In acquired thrombotic thrombocytopenic purpura (TTP), an immune-mediated
deficiency of the von Willebrand factor–cleaving protease ADAMTS13 allows unrestrained …

A number of strategies exist to design molecular materials based on self-assembled
peptides and their derivatives.[1] These include soft materials based on a variety of structural …

Essentials• An international collaboration provides a consensus for clinical definitions.• This
concerns thrombotic microangiopathies and thrombotic thrombocytopenic purpura (TTP).• …

Severe ADAMTS13 deficiency occurs in 13% to 75% of thrombotic microangiopathies
(TMA). In this context, the early identification of a severe, antibody-mediated, ADAMTS13 …

Factor H (FH) is the major regulatory protein of the complement alternative pathway, with a
structure consisting of a tandem array of 20 homologous units, called short consensus …

Background Thrombotic thrombocytopenic purpura is a thrombotic microangiopathy related
to a severe deficiency of ADAMTS13 (a disintegrin and metalloprotease with …