Objective MicroRNAs (miRNA) have recently emerged as a new class of modulators of gene
expression. In this study we investigated the expression, regulation, and function of miR‐155 …

Objective: Glucosamine sulfate (GS) is a commonly used drug for the treatment of
osteoarthritis. The mechanism of the action of this drug does, however, remain to be …

Osteoarthritis (OA) is a chronic joint disease characterized by cartilage degradation,
osteophyte formation, subchondral bone sclerosis, and synovitis. Systemic factors such as …

Besides its primary function in locomotion, skeletal muscle (SKM), which represents up to
half of human's weight, also plays a fundamental homeostatic role. Through the secretion of …

Abstract Purpose of the Review Idiopathic inflammatory myopathies are a heterogeneous
group of autoimmune disorders. The presence of different autoantibodies allows clinicians to …

Objectives The study aimed to develop evidence-based recommendations for the treatment
of rapidly progressive interstitial lung disease (RPILD) associated with the anti-Melanoma …

We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic
immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with …

OBJECTIVE: We previously reported that an increase of cartilage thickness is the earliest
measurable change by magnetic resonance imaging (MRI) in early stages of experimental …

Background: Enthesitis is a remarkable feature of ankylosing spondylitis (AS) not specifically
approached by the available measuring tools for the disease. Ultrasonography (US) has …

Objective The progressive early changes in cartilage and subchondral bone in an
experimental model of osteoarthritis (OA) were investigated with high-resolution magnetic …