[HTML][HTML] TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells

N Kobayashi, P Karisola, V Peña-Cruz, DM Dorfman… - Immunity, 2007 - cell.com
The T cell immunoglobulin mucin (TIM) proteins regulate T cell activation and tolerance.
Here we showed that TIM-4 is expressed on human and mouse macrophages and dendritic …

Clinical practice guidance for juvenile dermatomyositis (JDM) 2018-Update

I Kobayashi, S Akioka, N Kobayashi… - Modern …, 2020 - academic.oup.com
Juvenile dermatomyositis is the most common type of juvenile idiopathic inflammatory
myopathy mainly affecting the skin and proximal muscles. We have published the Japanese …

Clinical and laboratory features of fatal rapidly progressive interstitial lung disease associated with juvenile dermatomyositis

N Kobayashi, S Takezaki, I Kobayashi, N Iwata… - …, 2015 - academic.oup.com
Objective. Rapidly progressive interstitial lung disease (RP-ILD) is a rare but potentially fatal
complication of JDM. The aim of this study was to establish markers for the prediction and …

Somatic NLRP3 mosaicism in Muckle-Wells syndrome. A genetic mechanism shared by different phenotypes of cryopyrin-associated periodic syndromes

K Nakagawa, E Gonzalez-Roca, A Souto… - Annals of the …, 2015 - ard.bmj.com
Familial cold autoinflammatory syndrome, Muckle-Wells syndrome (MWS), and chronic,
infantile, neurological, cutaneous and articular (CINCA) syndrome are dominantly inherited …

Identification of severe combined immunodeficiency by T-cell receptor excision circles quantification using neonatal guthrie cards

Y Morinishi, K Imai, N Nakagawa, H Sato… - The Journal of …, 2009 - Elsevier
OBJECTIVE: To assess the feasibility of T-cell receptor excision circles (TRECs)
quantification for neonatal mass screening of severe combined immunodeficiency (SCID) …

Thalidomide as an immunotherapeutic agent: the effects on neutrophil-mediated inflammation

K Yasui, N Kobayashi, T Yamazaki… - Current …, 2005 - ingentaconnect.com
Thalidomide was developed in the 1950s as a sedative drug and withdrawn in 1961
because of its teratogenic effects, but has been rediscovered as an immuno-modifying drug …

TIM-4, a receptor for phosphatidylserine, controls adaptive immunity by regulating the removal of antigen-specific T cells

LA Albacker, P Karisola, YJ Chang… - The Journal of …, 2010 - journals.aai.org
Adaptive immunity is characterized by the expansion of an Ag-specific T cell population
following Ag exposure. The precise mechanisms, however, that control the expansion and …

Absence of memory B cells in patients with common variable immunodeficiency

K Agematsu, T Futatani, S Hokibara, N Kobayashi… - Clinical …, 2002 - Elsevier
The molecular basis of common variable immunodeficiency (CVID) is unknown. To assess
humoral immunity in CVID, we selected 24 patients with early or late onset of disease. X …

Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant Behçet's disease

T Shigemura, N Kaneko, N Kobayashi, K Kobayashi… - RMD open, 2016 - rmdopen.bmj.com
Objective Although Behçet's disease (BD) is a chronic inflammatory disorder of uncertain
aetiology, the existence of familial BD with autosomal-dominant traits suggests that a …

[HTML][HTML] Infliximab versus intravenous immunoglobulin for refractory Kawasaki disease: a phase 3, randomized, open-label, active-controlled, parallel-group …

M Mori, T Hara, M Kikuchi, H Shimizu, T Miyamoto… - Scientific reports, 2018 - nature.com
We compared the efficacy and safety of infliximab with intravenous immunoglobulin (IVIG), a
standard therapy, in a phase 3 trial (NCT01596335) for Japanese patients with Kawasaki …