Proteorhodopsins (PRs) found in marine microbes are the most abundant retinal-based
photoreceptors on this planet. PR variants show high levels of environmental adaptation, as …

Objectives Rheumatoid arthritis (RA) is an autoimmune disease strongly associated with the
major histocompatibility complex (MHC) class II allele DRB1* 04: 01, which encodes a …

A longstanding goal has been to find an antigen-specific preventive therapy, ie, a vaccine,
for autoimmune diseases. It has been difficult to find safe ways to steer the targeting of …

Myeloid cells can be beneficial as well as harmful in tissue regenerative responses. The
molecular mechanisms by which myeloid cells control this critical decision of the immune …

B cells undergo several rounds of selection to eliminate potentially pathogenic autoreactive
clones, but in contrast to T cells, evidence of positive selection of autoreactive B cells …

Background In response to the spread of the coronavirus disease 2019 (COVID-19), plenty
of control measures were proposed. To assess the impact of current control measures on the …

Transgenic mice expressing human major histocompatibility complex class II (MHCII) risk
alleles are widely used in autoimmune disease research, but limitations arise due to non …

The title furanocoumarin, C14H12O4 [systematic name: 9-hydroxy-2-(prop-1-en-2-yl)-2, 3-
dihydro-7H-furo [3, 2-g] chromen-7-one], crystallizes with two independent molecules (A and …

Infiltrating cells of the monocyte/macrophage lineage sense a variety of environmental cues
of injured tissue and integrate those into a repair response. The molecular determinants that …

Abstract Information on the Arbeitsgemeinschaft Dermatologische Forschung (ADF) Round
Table held in Bad Sassendorf, Germany from October 30-31 is presented. Topics discussed …