[HTML][HTML] Mechanism of action of colchicine in the treatment of gout

N Dalbeth, TJ Lauterio, HR Wolfe - Clinical therapeutics, 2014 - Elsevier
Purpose The aims of this article were to systematically review the literature about the
mechanism of action of colchicine in the multimodal pathology of acute inflammation …

Mechanisms of inflammation in gout

N Dalbeth, DO Haskard - Rheumatology, 2005 - academic.oup.com
The clinical manifestations of gout are due to interactions between monosodium urate
(MSU) crystals and local tissues. This review article outlines recent advances in the …

[HTML][HTML] A review of uric acid, crystal deposition disease, and gout

F Perez-Ruiz, N Dalbeth, T Bardin - Advances in therapy, 2015 - Springer
There has been increased interest in gout in both academic and clinical practice settings.
Several reasons may explain this. The prevalence of both hyperuricemia and gout has risen …

2012 American College of Rheumatology guidelines for management of gout. Part 1: systematic nonpharmacologic and pharmacologic therapeutic approaches to …

…, F Lioté, H Choi, JA Singh, N Dalbeth… - Arthritis care & …, 2012 - Wiley Online Library
Gout is a disorder that manifests as a spectrum of clinical and pathologic features built on a
foundation of an excess body burden of uric acid, manifested in part by hyperuricemia …

2020 American College of Rheumatology guideline for the management of gout

JD FitzGerald, N Dalbeth, T Mikuls… - Arthritis & …, 2020 - Wiley Online Library
Objective To provide guidance for the management of gout, including indications for and
optimal use of urate‐lowering therapy (ULT), treatment of gout flares, and lifestyle and other …

[PDF][PDF] 2015 gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative

T Neogi, TLTA Jansen, N Dalbeth… - Arthritis & …, 2015 - Wiley Online Library
Objective Existing criteria for the classification of gout have suboptimal sensitivity and/or
specificity, and were developed at a time when advanced imaging was not available. The …

2012 American College of Rheumatology guidelines for management of gout. Part 2: therapy and antiinflammatory prophylaxis of acute gouty arthritis

…, F Lioté, H Choi, JA Singh, N Dalbeth… - Arthritis care & …, 2012 - Wiley Online Library
In response to a request for proposal from the American College of Rheumatology (ACR),
our group was charged with developing nonpharmacologic and pharmacologic guidelines …

[HTML][HTML] Effects of allopurinol on the progression of chronic kidney disease

…, FG Brown, A Cass, P Clarke, N Dalbeth… - … England Journal of …, 2020 - Mass Medical Soc
Background Elevated serum urate levels are associated with progression of chronic kidney
disease. Whether urate-lowering treatment with allopurinol can attenuate the decline of the …

Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol

…, J Drake, C Frampton, N Dalbeth - Arthritis & …, 2012 - Wiley Online Library
Objective Allopurinol is the most commonly used urate‐lowering therapy in gout. Allopurinol
hypersensitivity syndrome (AHS) is a rare but potentially fatal adverse event. Dosing …

nail disease in psoriatic arthritis—clinically important, potentially treatable and often overlooked

L Williamson, N Dalbeth, JL Dockerty, BC Gee… - …, 2004 - academic.oup.com
Objectives. To examine the relationship between the severity of nail disease and
characteristics of psoriatic arthritis (PsA). We also wished to assess the clinical management …